Impact of GM-CSF signaling pathway-related genes on clinical outcome of children with juvenile myelomonocytic leukemiaN., YoshidaH., YagasakiY., XuK., MatsudaA., YoshimiY., TakahashiK., MatsumotoK., KatoJ., UeyamaH., InadaHaematologica...
We also delineated the signaling pathway mediating the effect of senescent cells on cancer cell motility. Results Our results indicate that senescent cells stimulated the migration of breast cancer cells through secretion of GM-CSF and bFGF, which in turn induced activation of the JNK pathway in ...
Therefore, we investigated the effects of the benzene metabolite, hydroquinone (HQ), on alterations in the GM-CSF signaling pathway in TF-1 erythroleukemia cells and human CD34+ BM cells. HQ treatment in TF-1 cells results in a strong proliferative response that is dependent on ERK activation...
总之,我们的研究结果揭示了一种CIS调节机制,该机制阐明了GM-CSF在MØ分化中的相反作用,并揭示了GM-CSF在控制过敏性炎症中的作用。 英文摘要 The cytokine granulocyte-macrophage-colony stimulating factor (GM-CSF) possesses the capacity to dif...
Correlation of Clinical Features With the Mutational Status of GM-CSF Signaling Pathway-Related Genes in Juvenile Myelomonocytic Leukemia NAO YOSHIDA, HIROSHI YAGASAKI, YINYAN XU, KAZUYUKI MATSUDA, AYAMI YOSHIMI, YOSHIYUKI TAKAHASHI, ASAHITO HAMA, NOBUHIRO NISHIO, HIDEKI MURAMATSU, NOBUHIRO WATANABE, KI...
Response of STAT5 Luciferase Reporter U937 Cell Line to human GM-CSF. Inhibition of GM-CSF-stimulated STAT5 signaling by anti-GM-CSF antibody (Clone #BVD2-21C11). You may also be interested in ● Required Accessories ONE-Step™ Luciferase Assay System Thaw Medium 8 Growth Medium 8A ...
GM-CSF is a survival factor for and activates the effector functions of granulocytes, monocytes/macrophages, and eosinophils (1, 2). GM-CSF promotes a Th1 biased immune response, angiogenesis, allergic inflammation, and the development of autoimmunity (3 - 5). It shows clinical effectiveness in...
colony stimulating factor 2 (granulocyte-macrophage), Csfgm, Gm-CSf, GMCSF, MGI-IGM Ave. Rating Submit a Review Cat # Size Price 740631 100 tests (270 µL) 95€ To purchase, view our LEGENDplex™ Mix and Match page Description These Mouse GM-CSF Capture Beads are suitable fo...
This biotinylated polyclonal antibody, in conjunction with PeproTech Polyclonal Anti-Murine GM-CSF (500-P65) as a capture antibody, allows the detection of at least 0.2-0.4 ng/well of Recombinant mGM-CSF.Western Blot: To detect mGM-CSF by Western Blot analysis this antibody can be used at ...
Furthermore, in the absence of ILCs, there was a significant reduction in other components of the GM-CSF signaling pathway, including Csf2rb and Csf2rb2 and the intracellular signaling molecule Jak2 (Figure S3D). Indeed, comparison of the transcriptome of macrophages cultured in the presence or...