Targeting GM‑CSF in inflammatory diseases (2016); GM-CSF inhibition reduces cytokine release syndrome andneuroinflammation but enhances CAR-T cell function in xenografts (2019); Humanigen, Coporate Presentation (2020); GM-CSF, IL-3, and IL-5 Family of Cytokines:Regulators of Inflammation (2019)...
英文摘要 The cytokine granulocyte-macrophage-colony stimulating factor (GM-CSF) possesses the capacity to differentiate monocytes into macrophages (MØs) with opposing functions, namely, proinflammatory M1-like MØs and immunosuppressive M2...
原始出处: Rosalie M. Sterner,et al. GM-CSF inhibition reduces cytokine release syndrome and neuroinflammation but enhances CAR-T cell function in xenografts. Blood 2018 :blood-2018-10-881722; doi: https://doi.org/10.118...
(2001) GM-CSF: a strong arteriogenic factor acting by amplification of monocyte function . Atherosclerosis 159 : 343–356Buschmann, I.R.; Hoefer, I.E.; van Royen, N.; Katzer, E.; Braun-Dulleaus, R.; Heil, M.; Kostin, S.; Bode, C.; Schaper, W. GM-CSF: A strong arterio...
function of mature blood cell Their gene recombinant human products have been widely applied to clinical practice The effects of G-GSF GM-CSF in clinical application are as follows 1 reducing malignant tumor chemotherapy-related neutropenia duration of neutropenia infections and resulting treatment delays...
agecolonystimulatingfactorisessentialfortheviabilityandfunctionof culturedmurineepidermalLangerhmlscells.JErpMed,1987,166: 1484.1498. 11sisM1.,BernhardH,ShiotaFM,eta1.Granulocyte.macrophagecolo ny-?sfimul~ingfactor:aneffectiveadjuvantforproteinandpeptide-?based vaccines.B1o0d.1996,88:202—210. ...
The GM-CSF gene encodes for a cytokine that regulates the production, differentiation, and function of macrophages and granulocytes. The active form of the protein exists as a homodimer in the extracellular space. This gene is located in a cluster of related genes at the chromosome region 5q31...
The GM-CSF gene encodes for a cytokine that regulates the production, differentiation, and function of macrophages and granulocytes. The active form of the protein exists as a homodimer in the extracellular space. This gene is located in a cluster of related genes at the chromosome region 5q31...
It also stimulates the differentiation of myeloid leukemic cells and controls eosinophil function in some instances. GM-CSF also enhances the functionality of mature cells, such as neutrophils. In neutrophils, GM-CSF potentiates degranulation, the release of oxygen and nitrogen radical ions, ...
应用：GM-CSF无内毒素重组蛋白可用于细胞培养、ELISA标准品和蛋白质印迹对照。Biotech Bovine GM-CSF/Bovine GM-CSF (Yeast-derived Recombinant Protein) 重组蛋白文献参考：Short communication: Effect of granulocyte-macrophage colony-stimulating factor on neonatal calf peripheral blood neutrophil function in vitro....