Targeting GM‑CSF in inflammatory diseases (2016); GM-CSF inhibition reduces cytokine release syndrome andneuroinflammation but enhances CAR-T cell function in xenografts (2019); Humanigen, Coporate Presentation (2020); GM-CSF, IL-3, and IL-5 Family of Cytokines:Regulators of Inflammation (2019)...
英文摘要 The cytokine granulocyte-macrophage-colony stimulating factor (GM-CSF) possesses the capacity to differentiate monocytes into macrophages (MØs) with opposing functions, namely, proinflammatory M1-like MØs and immunosuppressive M2...
原始出处: Rosalie M. Sterner,et al. GM-CSF inhibition reduces cytokine release syndrome and neuroinflammation but enhances CAR-T cell function in xenografts. Blood 2018 :blood-2018-10-881722; doi: https://doi.org/10.118...
(cytokine receptor modules,CRM),and relies on disulfide bond betweenconservative cysteine to keep the extracellur space structure.GM-CSF discerns and combines α chain throughcharge then induces β chain to join in, forms the intact complex of ligand and receptor.Through the function ofdisulfide ...
The regulation of the development and function of dendritic cell subsets by GM-CSF: more than a hematopoietic growth factor. Mol. Immunol. 52, 30–37 (2012). Article CAS PubMed Google Scholar Esashi, E. et al. The signal transducer STAT5 inhibits plasmacytoid dendritic cell development by...
In addition, GM-CSF altered the number and function of dendritic cell populations.Eyad M. HannaSatheesh K. SainathanKumar S. BishnupuriQizhi LuoRodney D. NewberryCourtney W. HouchenShrikant AnantBrian K DieckgraefeRegulatory peptides.
GM-CSF inhibition reduces cytokine release syndrome and neuroinflammation but enhances CAR-T cell function in xenografts (2019); Humanigen, Coporate Presentation (2020); GM-CSF, IL-3, and IL-5 Family of Cytokines: Regulators of Inflammation (2019); Aberrant pathogenic GM-CSF+ T cells and ...
应用:GM-CSF无内毒素重组蛋白可用于细胞培养、ELISA标准品和蛋白质印迹对照。Biotech Bovine GM-CSF/Bovine GM-CSF (Yeast-derived Recombinant Protein) 重组蛋白文献参考:Short communication: Effect of granulocyte-macrophage colony-stimulating factor on neonatal calf peripheral blood neutrophil function in vitro....
[4]Sterner R, Sakemura R, Cox M et al. (2019) GM-CSF inhibition reduces cytokinerelease syndrome and neuroinflammation but enhances CAR-T cell function inxenografts. Immunobiology And Immunotherapy 2019 Feb 14.doi.org/10.1182/BLOOD-2018-10-881722 ...
中国协和医科大学硕士学位论文重组人GM-CSF工程菌发酵工艺的研究姓名:杨**吉)申请学位级别:硕士专业:微生物学指导教师:**柏;徐维民20000501摘要粒一巨噬细胞集落刺激因子(GM—CSF)在细胞因子网络系统中具有免疫调节,抗肿瘤,抗感染等功能,对调节骨髓造血祖细胞的分化与增殖,加速骨髓移植病人的造血恢复,增强癌症病人对...