G-CSF/CSF3R signaling involves the recruitment of non-receptor protein tyrosine kinases and their dependent signaling pathways of serine/threonine kinases, tyrosine phosphatases, and lipid second messengers. These pathways converge to activate the families of STAT and C/EBP transcription factors. CSF3R...
G-CSF (granulocyte colony-stimulating factor) is an endogenous hematopoietic cytokine, produced by monocytes, fibroblasts, and endothelial cells, that is involved in the mobilization of granulocytes, stem, and progenitor cells from the BM into the...
immune response positive regulation of cell proliferation positive regulation of phosphatidylinositol 3-kinase signaling positive regulation of actin filament polymerization granulocyte differentiation positive regulation of protein binding positive regulation of peptidyl-serine phosphorylation positive regulation of tran...
signaling pathways, such as Akt and also the Janus family kinase-2 and signal transducer and activation of transcription-3 (Jak2-STAT3) pathway, thereby promoting survival, proliferation, differentiation and mobilisation of haematopoietic stem and progenitor cells. G-CSF is a cytokine that have been...
immune response positive regulation of cell proliferation positive regulation of phosphatidylinositol 3-kinase signaling positive regulation of actin filament polymerization granulocyte differentiation positive regulation of protein binding positive regulation of peptidyl-serine phosphorylation positive regulation of tran...
Colony-stimulating factors are cytokines. They work by activated intracellular (cell-to-cell) signaling pathways. This causes the targeted cells to proliferate and differentiate into specific kinds of cells. As mentioned, the specific kinds of cells resu
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产品类型:多因子检测 品牌:Thermo Fisher 货号:EPX01A-26034-901 规格:96 tests 价格:1 物种:小鼠 宿主:其它 抗体亚型:其它 荧光染料:其它 产品介绍 技术参数 相关产品 产品介绍 Immunoassay Kit Grade:Simplex Kit 测定范围:As determined for Lot 1: 1.4-5850 pg/mL ...
产品类型:多因子检测 品牌:Thermo Fisher 货号:EPX01A-36034-901 规格:96 tests 价格:1 物种:大鼠 宿主:其它 抗体亚型:其它 荧光染料:其它 产品介绍 技术参数 相关产品 产品介绍 Immunoassay Kit Grade:Simplex Kit 测定范围:As determined for Lot 1: 3.7-15000 pg/mL ...
SDF1A/CXCR4 signaling axis inhibits beta-2 integrin LFA-1 mediated adhesion of monocytes to ICAM-1 through LYN kinase. It also plays a protective role after myocardial infarction, induces down-regulation and internalization of ACKR3 expressed in various cells and stimulates the proliferation of ...