I. Macikova, A. Perzelova, P. Mraz, I. Bizik, J. Steno, GFAP-positive astrocytes are rare or absent in primary adult human brain tissue cultures, Biologia 64 (4) (2009) 833-839.Macikova, I.; Perzelova, A.; Mraz, P.; Bizik, I.; Steno, J. GFAP-positive astrocytes are ...
Long-term voluntary running models for Down syndrome (DS) reduce the number of GFAP-positive astrocytes and the levels of GFAP in the brain Previous studies have suggested the levels of GFAP increased [54] and the GFAP-positive astrocytes proliferated [55] in the brain of adult DS subjects. ...
Interestingly, during differentiation of KO NSCs there were no defects in mitochondrial function, and there were not changes in signaling molecules such as SMAD1/5/8, STAT3, and HES1 involved in differentiation of NSCs into astrocytes. In brain sections, GFAP-positive astrocytes were more sparsely...
GFAP可能是成熟与未成熟畸胎瘤的一种有效的鉴别指标。 5. GFAP+ astrocytes HHD no changes and there were no VIM + astrocytes in postmortem groups. 死后脑干损伤组gfap+星形胶质细胞无改变,创缘及创周无vim +星形胶质细胞出现。 单词专题
Recent studies indicate that in the adult, migrating SVZa-derived cells are ensheathed by astrocytes, although the function of these astrocytes has not been determined. To explore the possible role(s) of astrocytes in the rat SVZa and RMS, we examined the expression of astroglial-specific ...
Recent studies indicate that in the adult, migrating SVZa-derived cells are ensheathed by astrocytes, although the function of these astrocytes has not been determined. To explore the possible role(s) of astrocytes in the rat SVZa and RMS, we examined the expression of astroglial-specific ...
GFAP is one of the main components of the intermediate filament network in astrocytes and has been proposed as playing a role in cell migration, cell motility, maintaining mechanical strength, and in mitosis. Tissue specificity GFAP is expressed in central nervous system cells, predominantly in ...
Lesion sites associated with neurodegeneration can exhibit an array of gliosis characteristics from glial scarring with reduced astrocyte proliferation to activated, GFAP-positive astrocytes surrounding amyloid plaques (2). Furthermore, the GFAP gene is a target of single nucleotide polymorphisms in the...
Interestingly, we found that the cerebral vessels in APP/PS1 mice lacking apoA-I were associated with significantly more GFAP-positive astrocytes than cerebral vessels in APP/PS1 mice expressing apoA-I [30]. Given these previous observations of increased cerebral vessel pathology in apoA-I-deficient...
GFAP伪 is the canonical splice variant and is expressed in all GFAP-positive cells. In the human brain, the alternatively spliced transcript GFAP未 marks specialized astrocyte populations, such as subpial astrocytes and the neurogenic astrocytes in the human subventricular zone. We here show that ...