The major player of the stroma with respect to extracellular matrix deposition, maintenance, and remodeling is the fibroblast and its activated derivative, the myofibroblast. It has long been recognized that there is considerable variability to the fibroblast phenotype. The recent advent of new single...
Fibroblast and myofibroblast activation in normal tissue repair and fibrosis Fereshteh Sadat Younesi, Andrew E. Miller, Thomas H. Barker, Fabio M. V. Rossi & Boris Hinz Nature Reviews Molecular Cell Biology volume 25, pages 617–638 (2024)Cite this article 23k Accesses 57 Altmetric Metrics ...
Fibroblast to myofibroblast transition is enhanced by increased cell density Effects of elevated glucose levels on interactions of cardiac fibroblasts with the extracellular mat... [Fibroblast and myofibroblast in the granulation tissue]. Temporal elevation of type VI collagen and cardiac myofibroblast diffe...
intermediate, and malignant lesions. Fibroblasts are the most common cells in fibrous connective tissue and make procollagen, protoelastin, and glycosaminoglycans. Myofibroblasts are a differentiated cell type that are essential for wound healing, participating in tissue remodeling...
STAT-3 contributes to pulmo- nary fibrosis through epithelial injury and fibro- blast-myofibroblast differentiation. FASEB J 2016; 30: 129-140.Pedroza M, Le TT, Lewis K, Karmouty-Quintana H, To S, George AT, Blackburn MR, Tweardy DJ, Agarwal SK. STAT-3 contributes to pulmonary ...
et al. The myofibroblast at a glance. J. Cell Sci. 133, jcs227900 (2020). Article PubMed CAS Google Scholar Friedman, S. L., Sheppard, D., Duffield, J. S. & Violette, S. Therapy for fibrotic diseases: nearing the starting line. Sci. Transl. Med. 5, 167sr1 (2013). Article ...
Vol.:01345678913CellularandMolecularLifeSciences01875:3943–3961https://doi.org/10.1007/s00018-018-899-4REVIEWFibroblast‑to‑myofibroblasttransitionin bronchialasthmaMarta Michalik1 ·Katarzyna Wójcik‑Pszczoła1 ·Milena Paw1 ·Dawid Wnuk1 ·P
2. myofibroblast的测序与分群 参考文献,以Acta2, Myh11, Tagln确认为myofibroblast,对myofibroblast进行表征如下图。 3. Col13a1 matrix fibroblast的transcriptional signature 将这类细胞再聚类,分成两个群:Col13a1 和 Col14a1 matrix fibroblasts,对两组进行表征 ...
fibroblast Thesaurus Medical Encyclopedia Wikipedia Related to fibroblast:chondroblast,Fibrocyte,myofibroblast fi·bro·blast (fī′brə-blăst′) n. A cell that gives rise to connective tissue. fi′bro·blas′ticadj. American Heritage® Dictionary of the English Language, Fifth Edition. Copyright...
T., Blackburn, M. R., Tweardy, D. J., Agarwal, S. K. STAT-3 contributes to pulmonary fibrosis through epithelial injury and fibroblast-myofibroblast differentiation. 展开 关键词: STAT3 epithelial injury fibrosis myofibroblast DOI: 10.1096/fj.15-273953 被引量: 24 年份: 2016 ...