Myofibroblast-like cells and wound contraction in leech wound healing. Journal of Experimental Zoology, 275: 308-316.Huguet G, Molinas M. Myofibroblast-like cells and wound contraction in leech wound healing. J Exp Zool 1996;275:308 - 16....
In six cases of anterior capsular cataract, cells present in the subcapsular zone were investigated. In addition to organelles previously described, the cells were found to contain 7 nm and 15 nm filaments, suggestive of actin and myosin. The cells varied in shape from elongated or flat to rou...
The presence of these cells indicates that in vivo contraction of early callus is a mechanism that may occur in fractures so as to facilitate healing, as it does in soft tissue wound repair. 展开 关键词: Animals Rats Bony Callus Muscle, Smooth Rib Fractures Biological Markers Statistics, ...
Growth inhibition of myofibroblastlike ITO cells by endothelin-1: A cAMP-mediated effect involving inhibition of JUN kinase and MAP kinase pathways: 1INSERM U99, Hôpital Henri Mondor 94010 Créteil, France. 2Sanofi Recherche, 31036 Toulouse, France. 3University of North Carolina, Chapel Hill, ...
Endothelial-like cells in chronic thromboembolic pulmonary hypertension: crosstalk with myofibroblast-like cells Background Chronic thromboembolic pulmonary hypertension (CTEPH) is characterized by intravascular thrombus formation in the pulmonary arteries. Recently,... S Sakao,H Hao,N Tanabe,... - 《Respi...
Vascular cells may also differentiate into matrix-secreting contractile myofibroblasts to promote wound closure. Here, we characterize a PECAM1+/Sca1+ vascular cell population in mouse skin, which is highly enriched in wounds at the peak of neoangiogenesis and myofibroblast formation. These cells expr...
In endothelial cells, an antagonist effect between LPS-induced signaling and canonical TGF-β1 signaling was described; however, it has not been studied whether in CF and CMF the expression of α-SMA induced by TGF-β1 is antagonized by LPS and the mechanism involved. In adult rat CF and ...
Although common myofibroblast markers were expressed in low abundance, most of the targeted cells expressed myosin IIb, an embryonic form of smooth muscle myosin heavy chain that has previously been associated with myofibroblasts after reperfused MI. This study is the first to demonstrate AAV-mediated...
Pancreatic stellate cells: a starring role in normal and diseased pancreas an activated, myofibroblast-like phenotype that secretes excessive amounts of ECM proteins leading to the fibrosis of chronic pancreatitis and pancreatic cancer... MV Apte,RC Pirola,JS Wilson - 《Front Physiol》 被引量: 22...
In hypoxic cells however, the mechanisms that target HIFs for degradation are inhibited, allowing HIF-1α and HIF-2α to translocate to the nucleus. In the nucleus, both HIF-1α and HIF-2α heterodimerize with HIF-1β and regulate the expression of genes involved in oxygen homeostasis (11...