Receptors for the Fc portion of immunoglobulins (FcR) on murine oral mucosal T cellsheat conductionexact analytical solutiontransient problemmultiple layersThe incidence and distribution of immunoglobulin receptors on oral mucosal T cells were investigated. Enrichment of either Thy-1.2, L3T4 or Lyt-2.2...
A receptor for the Fc portion of immunoglobulin, derived from mouse or human cells, the receptor exhibiting the ability to bind to the Fc portion of mouse and human immunoglobulin and comprising a tra
Background:This gene encodes a receptor for the Fc portion of immunoglobulin G, and it is involved in the removal of antigen-antibody complexes from the circulation, as well as other responses, including antibody dependent cellular mediated cytotoxicity and antibody dependent enhancement of virus infec...
背景资料:ThisgeneencodesareceptorfortheFcportionofimmunoglobulinG,anditisinvolvedintheremovalofantigen-antibodycomplexesfromthecirculation,aswellasotherresponses,includingantibodydependentcellularmediatedcytotoxicityandantibodydependentenhancementofvirusinfections.Thisgene(FCGR3A)ishighlysimilartoanothernearbygene(FCGR3B)locat...
The Fc portion of immunoglobulin G (IgG) expresses paired oligosaccharides with microheterogeneities, which are associated with efficiencies of effector functions and with pathological states. A comparison of electrospray ionization mass spectrometry data obtained using a variety of Fc fragments derived from...
背景说明:FcγRIIB is a low affinity receptor that recognizes the Fc portion of IgG. The human CD32 group consists of FcγRIIA, FcγRIIB, and FcγRIIC proteins that share 94-99% sequence identity in their extracellular domains but differ substantially in their transmembrane and cytoplasmic ...
In polarized neutrophils, asymmetric distributions of membrane receptors, such as those for the Fc portion of immunoglobulin G (IgG) =-=[26]-=-, concanavalin A [27], succinyl-conA [15], and N-formyl peptides [28, 29], have been observed. These asymmetries have been suggested to be ...
Immune effector functions recruited through the Fc portion of immunoglobulin G (IgG) are increasingly recognised as an important component of HIV-1 protective immunity [1]. In murine and non-human primate models, Fc-mediated mechanisms have been demonstrated to augment the in vivo activity of broad...
While human-likeN-glycosylation of recombinant FVIII is known to be crucial for the clotting factor's quality and function, the particular glycosylation of the fused Fc portion has not been investigated in detail so far, despite its known impact on Fcγ receptor binding. Here, we analyzed theN...
It has been proposed that such antibody bipolar bridging could block access of the Fc portion of the anti-HSV1-specific IgG antibody to FcγR expressed on innate immune effector cells and thereby reduce classical ADCC and presumably provide a mechanism for immune evasion following HSV1 infection ...