Fc fragment of immunoglobulin G in normal human plasma and urine. Nature. 1967 May 13; 214 (5089):697–699.J. Berggard and H. Bennich, “Fc fragment of immunoglobulin in normal human plasma and urine,” Nature 214(5089):697 (1967)....
别称:Fc fragment of IgG binding protein; FC(GAMMA)BP; Fcgamma-binding protein antigen; FcgammaBP; FCGBP; FCGBP_HUMAN; Human Fc gamma BP; IgGFc-binding protein. 产品介绍: Fc(Ig恒定片段)受体可通过从循环中去除Ig包被的抗原复合物来确保宿主免受外来抗原(例如微生物和病原体)的侵害。 Fc受体存在于...
We further evaluate immunological properties of HSCs by examining the expression and function of the Fc fragment of immunoglobulin G ( IgG ) in HSCs. In this study, we document the presence of mRNAs for three Fc纬Rs in HSCs. Ligand binding assay indicated the existence of Fc纬Rs with ...
The interaction between the host antibody Fc region and Fc receptors is important in the immune defense against influenza virus infection. Fc fragment of IgG, low affinity IIa, receptor (FCGR2A) gene encodes Fcγ receptor IIA (FcγRIIA), which bindsimmune complexes. The association betweenFCGR2A...
目前,Fab抗体片段可以在实验室制备出来。在木瓜蛋白酶的作用下,人免疫球蛋白G(Immunoglobulin G,IgG)可以被降解为两个Fab片段及一个Fc片段(fragment crystallized, 结晶片段);在胃蛋白酶的额作用下,IgG可以被降解为一个F(ab’)2片段和一个pFc’片段。F(ab’)2片段可以进一步被还原,形成两个Fab’片段。
Papain digestion of 7S immunoglobulin G (IgG) produces two 3.5S Fab fragments and one 3.5S Fc fragment 1–8 . The Fab fragment contains one light chain and one Fd fragment and is still able to combine specifically univalently with antigen. The Fc fragment is a dimer of the carboxyl ...
别名CD32; CD 32;CD32 antigen; CD32A; CD32B; CD32C; CDw32; Fc gamma RII a; Fc fragment of IgG low affinity II receptor for (CD32); Fc fragment of IgG low affinity IIa receptor; Fc fragment of IgG low affinity IIa receptor for (CD32); Fc fragment of IgG low affinity IIb recept...
Key words Fc fusion protein ; Fc fragment of immunoglobulin ; Fc receptor 王宇恒,郭薇,王欣,王辰,高向东, 5、姚文兵 * 抗体类药物是当前药物研发的重点和热点,通常 能较快获得上市许可,并带来较大的商业成功。进入 21 世纪以来,美国 FDA 和欧洲药物管理局(European Medicines Agency,EMA)总共批准了约 20 ...
单克隆抗体由位于两臂末端的抗原结合片段(antigen-binding fragment,Fab)和结晶片段(crystalline fragment,Fc)组成。Fab主要特异性识别肿瘤相关抗原,进而调控下游的信号通路,而Fc段可以识别并结合表达Fc受体的免疫细胞以及血液中的补体,发挥Fc段效应功能。对Fc段...
别名FCG3A_HUMAN; CD 16; CD 16a; CD16A; CD16a antigen; CD16B; CD16b antigen; Fc fragment of IgG; Fc fragment of IgG low affinity IIIa receptor (CD16); Fc fragment of IgG, low affinity III, receptor (CD16); Fc fragment of IgG, low affinity IIIa, receptor (CD16); Fc fragment of...