Kotitschke R: Assessment of the Fc function in human immunoglobulins for intravenous administration. Multicenter study of the section “blood plasma constitutents” of the German Association for Transfusion Medicine and Immunohematology (DGTI). Infusionsther Transftisionsmed 20:93–95, 1993Kotitschke R...
An improved method for the determination of Fc function of immunoglobulins. Georgakopoulos T,Tatford O C,Tan C S,Gurevich V,Bertolini J. Vox Sanguinis . 2009Georgakopoulos T,Tatford O C,Tan C S,et al.An improved method for the determination of Fc function of immunoglobulins. Vox ...
They are likely to function as a substitution for the hydrophobic core to preserve an optimal lower hinge conformation for the receptor binding. Subtype specificities of FcγRIII receptor probably are determined by the length of the lower hinge regions of immunoglobulins, but not their amino acid ...
Function: Binds to the Fc region of immunoglobulins epsilon. High affinity receptor. Responsible for initiating the allergic response. Binding of allergen to receptor-bound IgE leads to cell activation and the release of mediators (such as histamine) responsible for the manifestations of allergy. The...
The chemistry, structure, and function of immunoglobulins Maria J.Gutierrez,StephenDesiderio, inClinical Immuno-Oncology, 2024 The structure of immunoglobulins Overall structure Immunoglobulin(Ig) and T-cell receptors (TCRs), produced by B- and T-lymphoid cells, respectively, are thespecific antigenrec...
The receptors for the Fc of immunoglobulins, Fc receptors (FcRs), link the humoral and cellular branches of the immune system, and they have important functions in the activation and down-modulation of immune responses. Balanced signalling through activating and inhibitory FcRs regulates the activity...
Structure and function of immunoglobulins immunoglobulin gene rearrangementclass switchingsomatic hypermutationImmunoglobulins are heterodimeric proteins composed of 2 heavy and 2 light chains. They can be... HW Schroeder,L Cavacini - 《Journal of Allergy & Clinical Immunology》 被引量: 735发表: 2010年...
We have developed and optimised a new flow-cytometric method for the measurement of the Fc function of intravenous immunoglobulin (IVlg) preparations, which is important in predicting the effector function of immunoglobulin (Ig) in such preparations. Ig was bound to a monocytic cell line, THP-1...
Here, the authors review the expression patterns and function of Fc receptors for IgG (FcγRs) on conventional dendritic cells (DCs), monocyte-derived DCs, plasmacytoid DCs and macrophages in the steady state and at sites of inflammation. They also discu
Function Binds to the Fc region of immunoglobulins epsilon. High affinity receptor. Responsible for initiating the allergic response. Binding of allergen to receptor-bound IgE leads to cell activation and the release of mediators (such as histamine) responsible for the manifestations of allergy. The ...