Antibody-forming cells were studied to determine whether they had receptors for the Fc portion of IgG(FcR). Spleen cells from mice immunized with horse red blood cells(HRBC) were assayed for anti-HRBC plaque-forming cells (PFC) after they were depleted by Ficoll-Hypaque density sedimentation of...
FcRn binds tightly to the Fc portion of IgG at acidic pH (pH 6.0) but not at physiological pH (pH 7.4). The hydrophobic interactions between FcRn and Fc are stabilized by salt-bridges that form between anionic residues on FcRn and titratable histidine residues of the IgG Fc region. ...
(fc), containing the H chain constant region. IgG antibody have enormous therapeutic potential and the Fc is for the development of therapeutic antibody. Although the antibody site is located in the terminal end of the human IgG molecule (part of the Fab fragment), the Fc portion has various...
亚型IgG 纯化方法affinity purified by Protein A 储存液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. 保存条件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. PubMedPubMed 产品介绍This gene encodes a receptor for the Fc portion of imm...
背景说明:FcγRIIB is a low affinity receptor that recognizes the Fc portion of IgG. The human CD32 group consists of FcγRIIA, FcγRIIB, and FcγRIIC proteins that share 94-99% sequence identity in their extracellular domains but differ substantially in their transmembrane and cytoplasmic ...
The interactions of antibodies with myeloid Fc纬 receptors and the complement system are regulated by an Asn297-linked glycan in the Fc portion of IgG. Alterations of serum IgG-Fc glycosylation have been reported in various autoimmune diseases, and correlate with treatment response and disease ...
The Fc portion of immunoglobulin G (IgG) expresses paired oligosaccharides with microheterogeneities, which are associated with efficiencies of effector functions and with pathological states. A comparison of electrospray ionization mass spectrometry data obtained using a variety of Fc fragments derived from...
The role of these amino acids is discussed in the context of the previously reported structures of rat FcRn and a complex of FcRn with the Fc portion of IgG.Daniel E VaughnChristina M MilburnDavid M PennyW.Lance MartinJennifer L Johnson...
抗原:IgG物种:兔宿主:山羊抗体亚型:IgG荧光染料:HRP加入购物车 产品介绍 技术参数 相关产品 产品介绍 产品介绍 Goat anti Rabbit IgG (Fc) antibody recognizes the Fc portion of rabbit IgG. Assay by IEP resulted in a single precipitin arc against anti-peroxidase, anti-goat serum, rabbit IgG, rabbit...
Human Fc gamma RIII: cloning, expression, and identification of the chromosomal locus of two Fc receptors for IgG. A cDNA clone encoding a human receptor for the Fc portion of IgG (Fc gamma R), Fc gamma RIII or CD16, was isolated from a human leukocyte library by a tran... G,A,...