HTS-compatible beta-lactamase transcriptional reporter gene assay for interrogating the heat shock response pathway NIH Chemical Genomics Center A quantitative high-throughput screen for modulators of IL-6 signaling: a model for interrogating biological networks us...
beta-Lactamase production by bacteria continues to be one of the main mechanisms of bacterial resistance to beta-lactam antibiotics, and it seems likely to remain so. beta-Lactamase inhibitors provide 1 strategy to overcome this mechanism of bacterial resistance. Although 3 beta-lactamase inhibitor/an...
In inflammatory process, during the innate immune response, various cells of the immune system (neutrophils, macrophages, lymphocytes) release mediators (cytokines, ROS etc.) that enhance the inflammatory process and activate the adaptive immunity. T Helper cells in turn activate various other type of...