In particular, the compounds can be in the β- lactam antibiotics (eg, imipenem, piperacillin or ceftazidime) together for confrontation since the inner β- lactamase presence within β- lactam antibiotic resistance microorganisms.T·A·布利扎德...
Beta-lactamaseinhibitors bind irreversibly to the catalytic site of beta-lactamase, preventing hydrolysis of the beta-lactam antibiotic. They also bind to bacterialpenicillinbinding proteins, increasing theantibacterial activityof the antibiotics.Clavulanic acidhas a chemical structure resembling the penicillin...
Beta-lactam antibiotics beta-lactam inhibitors Beta-lactam Ring Beta-lactam Ring Beta-lactam Ring Beta-Lactam Ring Records beta-lactamase beta-lactamase beta-lactamase beta-lactamase inhibitors Beta-Lactamase Negative Ampicillin-Resistant Beta-Lactamase Producing Organism ...
To prevent the destruction of these drugs by beta-lactamases, these antibiotics are very often administered with beta-lactamase inhibitors. Other modes of beta-lactam resistance by Acinetobacter include modification of penicillin binding proteins and the presence of drug efflux pumps Katzung (2001). ...
BETA-LACTAMANTIBIOTICS(inhibitorsofcellwallsynthesis)Theirstructurecontainsabeta-lactamring.Themajorsubdivisionsare:(a)penicillinswhoseofficialnamesusuallyincludeorendin“cillin”(b)cephalosporinswhicharerecognizedbytheinclusionof“cef”or“ceph”intheirofficialnames.(c)carbapenems(e.g.meropenem,imipenem)(d)mono...
β‐lactamase inhibitorhigher H.pylori eradication rateomeprazoleside effectstriple therapyObjectives. One-week triple therapy, a combination of acid suppression with two antibiotics, is the gold standard for anti- Helicobacter pylori treatment. There is increasing evidence of H. pylori resistance to ...
英文:Metallo-beta-lactamase 中文:金属-内酰胺酶 例句:Class B metallo-β-lactamases (MBLs) have a broad substrate spectrum and can catalyze the hydrolysis of virtually all β-lactam antibiotics with the exception of monobactams. They are not ...
Beta-lactam antibiotics beta-lactam inhibitors Beta-lactam Ring Beta-lactam Ring Beta-lactam Ring Beta-Lactam Ring Records beta-lactamase beta-lactamase beta-lactamase beta-lactamase beta-lactamase inhibitors Beta-Lactamase Negative Ampicillin-Resistant Beta-Lactamase Producing Organism beta-lactamase resistance...
The resistance of bacteria to the normally lethal action of beta-lactam antibiotics is largely due to the production of beta-lactamases that catalyze the hydrolysis of the beta-lactam. One class of these enzymes is a zinc-dependent metallo-beta-lactamase for which there are no clinically available...
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