Beta-lactam antibiotics beta-lactam inhibitors Beta-lactam Ring Beta-lactam Ring Beta-lactam Ring Beta-Lactam Ring Records beta-lactamase beta-lactamase beta-lactamase beta-lactamase inhibitors Beta-Lactamase Negative Ampicillin-Resistant Beta-Lactamase Producing Organism ...
These mutants overproduce the beta-lactamase constitutively, which results in an enzyme level that significantly exceeds the induced level. The induction process is probably not the cause of clinical failures associated with the use of beta-lactam antibiotics. It is concluded that the selection of ...
: any of a large class of natural and semisynthetic antibiotics (as the penicillins and cephalosporins) with a lactam ring Dictionary Entries Near beta-lactam beta interferon beta-lactam beta-lactamase See More Nearby Entries Cite this Entry Style “Beta-lactam.” Merriam-Webster.com ...
Sensitivity to beta-lactam antibiotics and production of beta-lactamase of gram-negative clinical isolatesMan'ko VM, Petrov RV, Sidorovich IG, Kraskina NA.doi:10.1007/BF00404587J. L. HoekstraA. W. HoubenE. E. StobberinghC. P. A. van Boven...
Beta-lactamase inhibitors are agents that enhance the effectiveness of beta-lactam antibiotics against bacteria producing beta-lactamases by causing irreversible inhibition of these enzymes. AI generated definition based on: xPharm: The Comprehensive Pharmacology Reference, 2007 ...
Beta-lactamases are the commonest cause of bacterial resistance to beta-lactam antibiotics. They have been classified phenotypically by their isoelectric p... B Bedenić - 《Lijec̆nic̆ki Vjesnik》 被引量: 3发表: 2004年 Extended-spectrum beta-lactamase in the urinary isolates of Enterobacte...
Beta-lactamaseinhibitor:ClavulanicacidSulbactamHydrolysisofthebeta-lactamringdestroystheantimicrobialactivityofabeta-lactamantibiotic.Theycontainabeta-lactamring,butbythemselves,donothaveantibacterialactivity.Instead,theybindtoandinactivatebeta-lactamases.Clavulanicacid+amoxicillin Vancomycin MechanismofactionItisatricyclicgl...
A novel beta-lactamase inhibitor has been isolated from Streptomyces clavuligerus ATCC 27064 and given the name clavulanic acid. Conditions for the cultiva... C Reading,M Cole - 《Antimicrob Agents Chemother》 被引量: 1051发表: 1977年 Monotherapy versus beta-lactam-aminoglycoside combination treatment...
Beta-lactamase lability and inducer power of newer beta-lactam antibiotics in relation to their activity against beta-lactamase-inducibility mutants of Pseudomonas aeruginosa. The interactions of imipenem, carbenicillin, cefotaxime, ceftriaxone, and azlocillin with the chromosomal beta-lactamase of Pseudomona...
there are major differences in the overall stabilization of these drugs post-acylation. It is likely that PBPs were the target of the evolution of this class of antibiotics, originally inStreptomyces cattleyaand in subsequent drug development25. This is exemplified by structural properties of the in...