Deveci O, Yula E, Tekin A. Frequency of extended spectrum beta-lactamase and resistance to antibiotics in Escherichia coli strains isolated from urinary cultures. J Clin Exp Invest 2010;1:182- 6.Deveci O, Yula E, Tekin A. Frequency of extended spectrum beta-lactamase and resistance to ...
beta-lactam antibiotic-resistant Staphylococcus aureus Beta-lactam antibiotics beta-lactam inhibitors Beta-lactam Ring Beta-lactam Ring Beta-lactam Ring Beta-Lactam Ring Records beta-lactamase beta-lactamase beta-lactamase beta-lactamase inhibitors
: any of a large class of natural and semisynthetic antibiotics (as the penicillins and cephalosporins) with a lactam ring Dictionary Entries Near beta-lactam beta interferon beta-lactam beta-lactamase See More Nearby Entries Cite this Entry Style “Beta-lactam.” Merriam-Webster.com ...
The meaning of BETA-LACTAMASE is any of various bacterial enzymes that inactivate the penicillins and cephalosporins by hydrolyzing them. How to use beta-lactamase in a sentence.
increasingly prevalent form of resistance, microbiologists have identified a new type of beta-lactamase enzyme, called inhibitor-resistant TEMs (IRTs), which can withstand the effects of beta-lactamase inhibitor compounds, further reducing the arsenal of drugs available to physicians facing resistant ...
Bacterial resistance to β-lactam antibiotics can be achieved by any of three strategies: the production of β-lactam-hydrolyzing β-lactamase enzymes, the utilization of β-lactam-insensitive cell wall transpeptidases, and the active expulsion of β-lactam molecules from Gram-negative cells by way...
The beta-lactam ring is subject to hydrolysis by beta-lactamases, enzymes produced by resistant bacterial strains. To prevent the destruction of these drugs by beta-lactamases, these antibiotics are very often administered with beta-lactamase inhibitors. Other modes of beta-lactam resistance by ...
Although YcbB is resistant to most beta-lactam antibiotics, it is susceptible to inhibition by carbapenem antibiotics such as meropenem and imipenem5. Carbapenem antibiotics are a subset of beta-lactam antibiotics which have previously been shown to inhibit other L,D-transpeptidases8. This class of...
Beta-lactamaseinhibitors bind irreversibly to the catalytic site of beta-lactamase, preventing hydrolysis of the beta-lactam antibiotic. They also bind to bacterialpenicillinbinding proteins, increasing theantibacterial activityof the antibiotics.Clavulanic acidhas a chemical structure resembling the penicillin...
Beta Lactamase TEM 1 is an enzyme encoded by the bla gene in E. coli, with its expression being constitutive. The resistance to β-lactam antibiotics is directly proportional to the number of copies of the bla gene and the enzyme synthesized. ...