BETA-LACTAMASE INHIBITORSDisclosed herein are α-aminoboronic acids and their derivatives which act as inhibitors of beta-lactamases. Also disclosed herein are pharmaceutical compositions comprising α-aminoboronic acids and methods of use thereof.Christopher J. BurnsRandy W. Jackson...
待解决 悬赏分:1 - 离问题结束还有 beta-lactamase inhibitors问题补充:匿名 2013-05-23 12:21:38 β-内酰胺酶抑制剂 匿名 2013-05-23 12:23:18 Beta-lactamase服用血管紧张素转化酶抑制剂 匿名 2013-05-23 12:24:58 betalactamase抗化剂 匿名 2013-05-23 12:26:38 β-内酰胺酶抑制剂 匿...
Disclosed herein are α-aminoboronic acids and their derivatives which act as inhibitors of beta-lactamases. Also disclosed herein are pharmaceutical compositions comprising α-aminoboronic acids and methods of use thereof. Inventors: Burns, Christopher J. (Malvern, PA, US) Jackson, Randy W. (Gl...
beta-lactamase inhibitors are generally less effective against chromosomally mediated type 1 beta-lactamases, manyCitrobacter,Enterobacter,Morganella, andSerratiaspp., andPseudomonas aeruginosaare resistant to them.Clavulanic acid,sulbactam, andtazobactamare beta-lactamase inhibitors. Whereas clavulanic acid is ...
Research programme: beta-lactamase inhibitors - Roche Alternative Names: FPI 1465 Latest Information Update: 28 Nov 2024 Price : €55 * Buy Profile Note: Adis is an information provider. We do not sell or distribute actual drugs. Final gross price and currency may vary according to...
The β-Lactamase Inhibitor Screening Kit is a rapid, simple and sensitive assay that is suitable for high throughput screening of β-Lactamase inhibitors. βL activity is measured by hydrolyzing a chromogenic cephalosporin called nitrocefin, producing a colorimetric product (A490), proportional to the...
Beta-lactamase inhibitors such as clavulanic acid, sulbactam, and tazobactam were introduced to overcome the actions of beta-lactamases. These inhibitors work by binding to the active site on the beta-lactamase enzyme, thus preventing binding and hydrolysis of the beta-lactam antibiotic.25 Extended ...
英文:Metallo-beta-lactamase 中文:金属-内酰胺酶 例句:Class B metallo-β-lactamases (MBLs) have a broad substrate spectrum and can catalyze the hydrolysis of virtually all β-lactam antibiotics with the exception of monobactams. They are not ...
Ingo HallerHanno WildWolfgang HartiwgUSUS5108747 * 1989年9月27日 1992年4月28日 Bayer Aktiengesellschaft Stable oxpenem-3-carboxylic acids as beta-lactamase inhibitorsUS5108747 * Sep 27, 1989 Apr 28, 1992 Bayer Aktiengesellschaft Stable oxpenem-3-carboxylic acids as beta-lactamase inhibitors...
The in vitro activities of the beta-lactamase inhibitors YTR 830, clavulanate, and sulbactam combined with six beta-lactams against 88 beta-lactamase-producing anaerobes were determined. When combined with the beta-lactams, the three beta-lactamase inhibitors showed no synergy against the 10 Bacteroide...