However, recent structural upgrades of class A beta-lactamases (e.g. TEM, SHV) have extended their spectrum (extended-spectrum beta-lactamases and carbapenemases [Sme, NMC-A, IMI-1]) and have brought about the possibility of beta-lactamase-inhibitor resistance. Furthermore, the mobilisation and...
beta-lactamase-inhibitor网络内酰胺酶抑制剂 网络释义 1. 内酰胺酶抑制剂 β-内酰胺酶抑制剂(Beta-lactamase inhibitor):舒巴坦匹酯(Sulbactam pivoxil) 治小儿抗多动症药(Anti-hyperactivity agents):托…www.siia.ac.cn|基于1 个网页© 2025 Microsoft 隐私声明和 Cookie 法律声明 广告 帮助 反馈...
Concomitant use of a beta-lactamase inhibitor (clavulanate) extends the spectrum of activity of amoxicillin to include beta-lactamase producing strains of H. influenzae, methicillin-susceptible Staphylococcus aureus, and anaerobic bacteria. Extended spectrum beta-lactams, such as piperacillin and ticar...
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Beta-lactamase inhibitor combinations Old and recently developedcephalosporinsare threatened by ever evolving new beta-lactamases [24]. To rescue or at least improve the activity of cephalosporins, the well-known and established practice of using beta-lactamase inhibitor combinations has been revived and...
More detailed studies on the interaction of the Ravasio β-lactamase with clavulanic acid demonstrated that the enzyme had high affinity for the inhibitor (Ki= 0.07 mol/L) and was rapidly inhibited (t = 21 sec, kinhib. = 0.033/sec). Two types of enzyme-inhibitor complex were formed, a ...
Combining ampicillin with an irreversible β- lactamase inhibitor such as sulbactam is a promising technique for controlling infections due to resistant organisms. The combination not only restores the effectiveness of ampicillin against species that have acquired resistance to it, but it can extend the...
beta-lactamase inhibitors Beta-Lactamase Negative Ampicillin-Resistant Beta-Lactamase Producing Organism beta-lactamase resistance beta-lactamase resistance beta-lactamase resistance beta-lactamase resistance beta-lactamase resistance beta-lactamase resistance ...
54. is a broad spectrum beta lactamase inhibitor 55. for gram negative bacteria infection in patients with penicillin allergy The 56. dose showed a double sulfur disulfide reaction A. cefazolin, B., sulbactam, C., cefuroxime, D., cefoperazone, ...
Piperacillin/tazobactam is a beta-lactam/beta-lactamase inhibitor combination with a broad spectrum of antibacterial activity encompassing most Gram-positi... CM Perry,A Markham - 《Drugs》 被引量: 279发表: 1999年 Outbreak of nosocomial infections due to extended-spectrum beta-lactamase-producing stra...