aEnzyme-substrate interactions at six sugar residue-binding subsites of the lysozyme active site 酶底物互作用在溶菌酶活跃站点的六糖残滓束缚的subsites [translate] 英语翻译 日语翻译 韩语翻译 德语翻译 法语翻译 俄语翻译 阿拉伯语翻译 西班牙语翻译 葡萄牙语翻译 意大利语翻译 荷兰语翻译 瑞典语翻译 希腊语...
A. Fernández GarcíaP. ButzR. LindauerB. TauscherFernandez, G. A. et al. (2002): Enzyme-Substrate Specific Interactions: In Situ Assessments Under High Pressure. S. 189-192. In: R. Hayashi (Hrsg.): Trends in High Pressure Bioscience and Biotech- nology: Proc. First International ...
The solvent effect in enzyme-substrate interactions: models of carboxypeptidase - Venanzi, Weinstein, et al. - 1982Venanzi, C. A., Weinstein, H., Corongiu, G., and Clementi, E. The solvent effect in enzyme-substrate interactions: models of carboxypeptidase. Int. J. Quantum Chem. QBS9: ...
Chapter 1 The energetics and specificity of enzyme—substrate interactions Life is a dynamic process, which depends upon the interaction among inanimate molecules. Living organisms have the capacity to utilize external energy and matter to maintain and propagate them. The interactions between substrate an...
Students interpret molecular representations depicting such interactions by determining the complementarity between enzyme and substrate by focusing upon charge and hydrogen bonding, but with a disregard for stereochemistry. © 2014 by The International Union of Biochemistry and Molecular Biology, 42(3):...
Allosteric interactions also play a part in feedback control of enzyme activity. In biosynthetic pathways, groups of enzymes frequently work together in sequential order to carry out metabolic processes. The reaction product of the first reaction quickly becomes the substrate of the second, and so ...
We have sought to determine whether the main source of enzyme deactivation is from enzyme-substrate interactions or other interactions of the enzyme in solution that are unrelated to the substrate (termed here as non-specific deactivation). To accomplish this, a series of tests were performed to ...
biochemical methods in detail, leading to the hypothesis of a three-step model of the cleavage process. The first step is the formation of the enzyme-substrate (ES) complex (Fig.1, species 1), and it has been proposed that the enzyme may use active site interactions to orient the β-...
we discovered potent and highly specific small-molecule inhibitors that alter IDE’s substrate selectivity. X-ray co-crystal structures, including an IDE-ligand-glucagon ternary complex, revealed substrate-dependent interactions that enable these inhibitors to potently block insulin binding while allowing ...
In many cases, the concomitant protein–enzyme and protein–cosubstrate interactions can mask modification-specific thermal stability changes of the substrates. This problem is addressed in our method of System-wide Identification of Enzyme Substrates by Thermal Analysis (SIESTA). SIESTA identifies specifi...