their biological relevance often remains elusive, especially in pathophysiological contexts such as cancer. In this study, we find that the tumor marker CD166/ALCAM (Activated LeukocyteCellAdhesionMolecule) is a clathrin-independent cargo. We show that endophilin-A3—but neither A1 nor A2 isoforms—f...
Since KCa2.3 specific currents could be increased in PC12 cells transfected with Endophilin A3 with DC-EBIO (30 u00b5M), a known SK-channel activator, these data also implicate that Endophilin A3 did not significantly remove KCa2.3 channels from the membrane but changed the sensitivity of the...
Heike JgerCellular Physiology and BiochemistryJanbein M, Abo Quader M, Hoppner AC, Gruner I, Wanker E, Walter S, Kuppers E, Grissmer S, Jager H (2014). Evidence for the Interaction of Endophilin A3 with Endogenous KCa2.3 Channels in PC12 Cells. Cell Physiol Biochem 34:474-490....