We show that endophilin-A3—but neither A1 nor A2 isoforms—functionally associates with CD166-containing early endocytic carriers and physically interacts with the cargo. Our data further demonstrates that the three endophilin-A isoforms control the uptake of distinct subsets of cargoes. In addition,...
their biological relevance often remains elusive, especially in pathophysiological contexts such as cancer. In this study, we find that the tumor marker CD166/ALCAM (Activated LeukocyteCellAdhesionMolecule) is a clathrin-independent cargo. We show that endophilin-A3—but neither A1 nor A2 isoforms—f...
Heike JgerCellular Physiology and BiochemistryJanbein M, Abo Quader M, Hoppner AC, Gruner I, Wanker E, Walter S, Kuppers E, Grissmer S, Jager H (2014). Evidence for the Interaction of Endophilin A3 with Endogenous KCa2.3 Channels in PC12 Cells. Cell Physiol Biochem 34:474-490....