Endothelial cell migration, proliferation and survival are triggered by VEGF-A activation of VEGFR2. However, how these cell behaviors are regulated individually is still unknown. Here we identify Endophilin-A2 (ENDOA2), a BAR-domain protein that orchestrates CLATHRIN-independent internalization, as a...
《Endophilin A2 调控炎症性肠病发生及机制研究》是依托中山大学，由贺青担任项目负责人的面上项目。中文摘要 目前临床治疗炎症性肠病的效果仍不满意，主要与该类疾病发病机制不清有关。我们前期利用基因芯片技术筛查发现 炎症性肠病患者结肠粘膜endophilin A2蛋白表达降低，而且endophilin A2 转基因小鼠可对抗葡聚糖硫酸...
产品名称:Endophilin-A2 ELISA Kit 检测范围:0.78-50 ng/mL 保存条件:2-8℃低温保存 保质期:6个月,所有试剂盒均提供批次。 试剂盒成分:酶标板,试剂,标准品等。 标本要求 1.标本采集后尽早进行提取,提取按相关文献进行,提取后应尽快进行实验。若不能马上进行试验,可将标本放于-20℃保存,但应避免反复冻融。
Annexin A2 ELISA Kit 价格: ￥2350/瓶 产品详情: 参数规格产品名称:Annexin A2 ELISA Kit 检测范围:0.625-40 ng/mL 保存条件:2-8℃低温保存保质期:6个月,所... 包装规格:48T/96T 用途:产品仅用于科研 货号:BK-F98593 品牌:帛科 产地:进口、国产 样本:Annexin A2 ELISA Kit elisa相关产品报价 更多> ...
《Endophilin A2参与调控血小板活化及血栓形成的机制研究》是依托中山大学，由吴倩倩担任项目负责人的青年科学基金项目。中文摘要 我们预实验发现endophilin A2转基因小鼠鼠尾出血时间延长，血小板粘附聚集能力降低，endophilin A2与血小板表面胶原受体integrin β1和GPVI有直接结合，提示endophilin A2可能是调控integrin β1...
A Competitive ELISA, Coated with Antibody ELISA kit for the detection of Gallus gallus, Chicken, Endophilin-A2, Endophilin-2, SH3 domain-containing GRB2-like protein 2, SH3p8, SH3GL1, SH3P8
《Endophilin A2下调在代谢紊乱导致内皮功能障碍中的作用及机制》是依托中山大学，由周家国担任项目负责人的面上项目。中文摘要 我们前期工作发现endophilin A2与eNOS相互结合，下调endophilin A2降低eNOS表达，高脂血症endophilinA2表达减少，提示endophilin A2可能是高脂血症诱导内皮功能障碍的关键因素，但...
We then used whole-cell recording to examine whether endophilin A2 could regulate TMEM16A CaCC activity in BASMCs and found that knockdown of endophilin A2 significantly enhanced CaCC activity, whereas overexpression of endophilin A2 produced the opposite effect. Overexpression of endophilin A2 did not...
Here we identify Endophilin-A2 (ENDOA2), a BAR-domain protein that orchestrates CLATHRIN-independent internalization, as a critical mediator of endothelial cell migration and sprouting angiogenesis. We show thatknockout mice exhibit postnatal angiogenesis defects and impaired front-rear polarization of ...