样本: Endophilin-A2 ELISA Kit 检测方法: 详见说明书 应用: ELISA 检测限: 0.78-50 ng/mL 货号: BK-F99653 是否进口: 是 选型: 产品规格:96T/48T 96T指可以做94个标本-2个标准对照-84个样本 48T指可以做47个标本-1个标准对照-42个样本参数规格 产品名称:Endophilin-A2 ELISA Kit 检测范围:0.78...
《Endophilin A2下调在代谢紊乱导致内皮功能障碍中的作用及机制》是依托中山大学,由周家国担任项目负责人的面上项目。中文摘要 我们前期工作发现endophilin A2与eNOS相互结合,下调endophilin A2降低eNOS表达,高脂血症endophilinA2表达减少,提示endophilin A2可能是高脂血症诱导内皮功能障碍的关键因素,但...
Endophilin A2, the sole endophilin A family member expressed in hematopoietic cells, regulates various aspects of membrane dynamics, including autophagy and endocytosis. Recent studies in rodents highlight the essential role of endophilin A2 in modulating immune responses. Here we report a homozygous ...
A Competitive ELISA, Coated with Antibody ELISA kit for the detection of Gallus gallus, Chicken, Endophilin-A2, Endophilin-2, SH3 domain-containing GRB2-like protein 2, SH3p8, SH3GL1, SH3P8
《Endophilin A2 调控炎症性肠病发生及机制研究》是依托中山大学,由贺青担任项目负责人的面上项目。中文摘要 目前临床治疗炎症性肠病的效果仍不满意,主要与该类疾病发病机制不清有关。我们前期利用基因芯片技术筛查发现 炎症性肠病患者结肠粘膜endophilin A2蛋白表达降低,而且endophilin A2 转基因小鼠可对抗葡聚糖硫酸...
Here we identify Endophilin-A2 (ENDOA2), a BAR-domain protein that orchestrates CLATHRIN-independent internalization, as a critical mediator of endothelial cell migration and sprouting angiogenesis. We show thatknockout mice exhibit postnatal angiogenesis defects and impaired front-rear polarization of ...
《Endophilin A2参与调控血小板活化及血栓形成的机制研究》是依托中山大学,由吴倩倩担任项目负责人的青年科学基金项目。中文摘要 我们预实验发现endophilin A2转基因小鼠鼠尾出血时间延长,血小板粘附聚集能力降低,endophilin A2与血小板表面胶原受体integrin β1和GPVI有直接结合,提示endophilin A2可能是调控integrin β1...
细胞血管新生采用Endophilin A2基因敲除小鼠和内皮特异性转基因小鼠,分别建立小鼠后肢缺血模型,应用免疫印迹,免疫荧光,免疫组化,PCR等研究方法,探讨了Endophilin A2对于血管生成的体内作用.同时建立VEGF诱导的人脐静脉内皮细胞模型,检测人脐静脉内皮细胞的迁移能力及管腔形成能力,进一步验证Endophilin A2对于血管生成的体外作用...
Endophilin A2 (EA2), encoded by the src-homology 3-domain GRB2-like 1 (SH3GL1) gene, is a member of the endophilin A family, which consists of an N-terminal BAR domain that can sense and induce membrane curvature, and a C-terminal SH3 domain responsible for protein–protein interaction...