Endophilin-A1是一种广泛表达于脑的突触前神经终末的胞浆蛋白,在突触囊泡的内吞回收,尤其是网格蛋 白介导的囊泡内吞(CMVE)过程中起重要作用。研究认为其本身可能调节Aβ的生成,也可能通过CMVE来影响脑内Aβ 的生成与释放,提示其与AD的发病有关。此外,endophilin-A1在糖尿病认知功能损害的大鼠脑内表达下调。
Furthermore, our study revealed that Syt11 has direct but Ca2+-independent binding with endophilin A1 (EndoA1), a membrane curvature sensor and endocytic protein recruiter, with high affinity. EndoA1-knockdown significantly reversed Syt11-KO phenotype, identifying EndoA1 as...
英文名称:SH3GL2/Endophilin A1 英文别名:产品应用:Human,Mouse,Rat,Dog,Cow,Horse,Rabbit,Guinea Pig,Cat,Elisa=1:500-1000,IHC-P=1:200-800,IHC-F=1:100-500,IF=1:100-500,ICC=1:100-500, 抗体中文名称:(胞吞蛋白Endophilin 1抗体) 抗体英文名称:[SH3GL2/Endophilin A1] ...
糖尿病大鼠海马endophilin-A1和dynamin-1的表达研究
Synonyms CNSA2, EEN B1, Endophilin 1, Endophilin A1, SH3 domain GRB2 like 2, SH3 domain protein 2A, SH3D2A, SH3GL2, SH3P4 Calculated Molecular Weight 39.8 kDa Observed Molecular Weight 40 kDa GenBank Accession Number BC032825 Gene Symbol Endophilin 1 Gene ID (NCBI) 6456 RRID AB_2187...
Together, these results reveal a novel function of postsynaptic endophilin A1 in spine morphogenesis, stabilization and synaptic function through the regulation of p140Cap. Keywords: endophilin A1; p140Cap; spine morphogenesis; actin cytoskeleton; synapse formation Cell Research (2015) 25:496-516. ...
Endophilin A1 (EP) is a protein enriched in synaptic terminals that has been linked to Alzheimer’s disease (AD). Previous in vitro studies have shown that EP can bind to a variety of proteins, which elicit changes in synaptic transmission of neurotransm
retrolinkin and endophilin A1的抗体。to 表示是，或者与之相对应。
SH3GL2/Endophilin A1 基本信息更多信息 中文名称: SH3GL2/Endophilin A1 中文同义词: 胞吞蛋白ENDOPHILIN 1抗体 英文名称: SH3GL2/Endophilin A1 英文同义词: SH3GL2/Endophilin A1 CAS号: 分子式: 分子量: 0 EINECS号: Mol文件: Mol File SH3GL2/Endophilin A1 信息错误报告 提交 ...
Earlier studies have found that endophilin A1 binds to the TIL of β1-AR with a dissociation constant of 47 nM (16). This interaction has been hypothesized to be a key element in the trafficking of this GPCR upon activation. Consequentially, we asked if this strong binding interaction would...