1. Now it is believed that Parkin functions as an E3 ubiquitin protein ligase which involves in protein s ubiquitination. 现认为Parkin行使泛素蛋白连接酶功能,参与蛋白质的泛素化过程。更多例句>> 2) Ubiquitin-protein ligases(E3) 泛素-蛋白连接酶 ...
别称:e3 ubiquitin-protein ligase parkin elisa kit 适应种属:人源 规格:96t 存储:在2-8℃存储6个月 uniprot id:o60260 应用:人e3泛素蛋白连接酶parkin(park2)酶联免疫elisa试剂盒可以在体外定量测定血浆,组织匀浆和其他生物液体中的人e3泛素蛋白连接酶parkin(park2)浓度. 检测方法:双抗夹心法 检测范围:0.156...
Parkin 为 UPS 系统中的一种 RING⁃between⁃RING E3 连接酶,介导底物蛋白的泛素化和 Aβ 蛋白的降解。Lonskaya 团队研究发现,E3 泛素连接酶 Parkin 可以促进细胞内 Aβ 聚合物的降解,降低细胞内 Aβ 的水平,恢复受损的蛋白酶体活性,并通过 UPS 途径进一步增加...
K33-1 inked polyubiquitination of coronin 7 by Cul3-KLHL20 ubiquitin E3 ligase regulates protein trafficking. Mol Cell, 2014, 54:586-600 Rajsbaum R, Vcrstccg GA, Schmid S, et al. Unanchored K48-1inked polyubiq uitin synthesized by the E3-ubiquitin ligase TR1M6 sti mu la tes the ...
Parkin functions as an E2-dependent ubiquitin– protein ligase and promotes the degradation of the synaptic vesicle-associated protein, CDCrel-1 Parkinson's disease is a common neurodegenerative disorder in which familial-linked genes have provided novel insights into the pathogenesis of this disord.....
英文名字 Recombinant Human E3 ubiquitin-protein ligase parkin (PRKN) 供应商 Biomatik 产品货号 RPC21786 产品报价 ¥询价/20ug ¥询价/100ug ¥询价/1mg 产品说明书 点击查看 购买方式 银行转账、电汇、支票、现金,在线支付宝及网银支付,或直接与我们电话联系400-6800-868...
AR JP ; E3 ubiquitin ligase; E3 ubiquitin protein ligase parkin; E3 ubiquitin-protein ligase parkin; FRA6E; LPRS 2; LPRS2; PARK 2; Park2; Parkin 2; Parkinson disease (autosomal recessive juvenile) 2; Parkinson disease (autosomal recessive; juvenile) 2; parkin; Parkinson disease pr...
英文名称:Recombinant Rat E3 ubiquitin-protein ligase parkin (Park2)Recombinant Rat E3 ubiquitin-protein ligase parkin (Park2) is available 1 time 来自 Mybiosource labs,中文名称:重组大鼠E3泛素蛋白连接酶parkin(Park2)重组大鼠E3泛
Parkin is an E3 ubiquitin-protein ligase initially thought to be involved in the ubiquitin-proteasome pathway but with emerging roles in a growing number of non-proteolytic processes. Genetics supports the idea that loss of Parkin function triggers disease. However, no unifying mechanism of loss ...
疾病简介:副伤寒,又称为副伤寒b,与沙门氏菌病和伤寒有关,症状包括便秘、发热和腹痛。与副伤寒相关的基因是PRKN(Parkin RBR E3 Ubiquitin Protein Ligase),其相关通路/超级通路包括先天免疫系统和MIF介导的糖皮质激素调节。在该疾病的背景下,已经提到了疫苗和免疫因子。附属组织包括皮肤和骨髓,相关表型是合成致死与ML...