基因名全称parkin RBR E3 ubiquitin protein ligase 蛋白名全称E3 ubiquitin-protein ligase parkin 推荐稀释比 Western blot(WB) 1:500~2000 Immunohistochemistry in paraffin section (IHC) 1:50~400 Immunocytochemistry 1:50~400 (Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA re...
Parkin (Park2), a RING-between-RING-type E3 ubiquitin ligase, has been implicated in regulating NF-κB. Mutations in Parkin are associated with Parkinson’s disease. Here we investigated the interaction of Parkin with Receptor-interacting protein kinase 1 (RIPK1) kinase, a key mediator of mult...
Parkin, PARK2, Parkinson disease protein 2, Parkin RBR E3 ubiquitin-protein ligase, EC:2.3.2.31Overview Tested Applications Product Information Publications (248) Protocols Reviews (2) Related Products (6) Print datasheet MSDS Validation Data Gallery Filter: AllWBIHCIF-PIF/ICC WB analysis using...
Outline Abstract Keywords 1. Introduction 2. Ubiquitin 3. Proteasome 4. Protein quality control and Parkinson's disease 5. Parkin 6. Perspective ReferencesShow full outline Cited by (107) Figures (3) Tables (1) Table 1 Biochimica et Biophysica Acta (BBA) - Molecular Cell Research...
Cited in 247 publications. PARK2/Parkin antibody for WB, IHC, IF/ICC, IF-P, ELISA and reacts with human, mouse, rat.
Mutations in the gene encoding for the E3 ubiquitin ligase Parkin are associated to a rare form of familiar autosomal recessive Parkinsonism. Despite decades of research on the Parkin protein, whose structure has been recently solved, little is known about the specific signalling pathways that lead ...
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英文名称:Recombinant Rat E3 ubiquitin-protein ligase parkin (Park2)Recombinant Rat E3 ubiquitin-protein ligase parkin (Park2) is available 1 time 来自 Mybiosource labs,中文名称:重组大鼠E3泛素蛋白连接酶parkin(Park2)重组大鼠E3泛
Mutations in the PTEN-induced kinase 1 (PINK1) and Parkin RBR E3 ubiquitin-protein ligase (PARKIN) genes are associated with familial forms of Parkinson’s disease (PD). PINK1, a protein kinase, and PARKIN, an E3 ubiquitin ligase, control the specific elimination of dysfunctional or superfluous...
Mutations in the E3 ubiquitin ligase parkin (PARK2, also known as PRKN) and the protein kinase PINK1 (also known as PARK6) are linked to autosomal-recessive juvenile parkinsonism (AR-JP)1,2; at the cellular level, these mutations cause defects in mitopha