DNA-binding motif. Prendergast,GC,Ziff,EB. Nature . 1989Prendergast GC, Ziff EB. DNA-binding motif [letter]. Nature 1989; 341: 392.GEORGE PRENDERGAST,EDWARD B. ZIFF.DNA-binding motif. Nature . 1989Prendergast,G.C. and Ziff,E.B. (1989) DNA binding motifs. Nature, 341, 392....
The helix-hairpin-helix DNA-binding motif: a structural basis for non-sequence-specific recognition of DNA. One, two or four copies of the 'helix-hairpin-helix' (HhH) DNA-binding motif are predicted to occur in 14 homologous families of proteins. The predicted DN... AJ Doherty,LC Serpell...
Some proteins contain more than one distinct DNA-binding motif that allows them to make different types of interaction with a singlebinding site. One example is the lymphocyte-enhancing factor (LEF-1) transcription factor in which sequence-specific binding is mediated by anhigh mobility group(HMG)...
functional gene set or many of them are found. Increasing the length of the motif to 8 bp seems however to increase the specificity of the motif repartition by comparison with 6 and 7 bp-long motifs (Figure5.Aand5.B). Here, we are facing the usual trade-off sensitivityvs. specificity,...
While mapping these relationships between TFs is important for understanding their context-specific functions, existing approaches either rely on DNA binding motif predictions, interrogate one TF at a time, or study individual TFs in parallel. Here, we introduce paired yeast one-hybrid (pY1H) assays...
The sequences of most of the YY1 binding sites are identical to the consensus sequences of the known YY1 binding motif, which display very high levels of affinity to YY1 protein [10]. However, one binding site, the 3rd one of all the vertebrates except urochordates, shows a slight ...
The helix-hairpin-helix DNA-binding motif: a structural basis for non-sequence-specific recognition of DNA. One, two or four copies of the 'helix-hairpin-helix' (HhH) DNA-binding motif are predicted to occur in 14 homologous families of proteins. The predicted DN... AJ Doherty,LC Serpell...
The histone fold motif has previously been identified as a structural feature common to all four core histones and is involved in both histone-histone and histone-DNA interactions. Through the use of a novel motif searching method, a group of proteins containing the histone fold motif has been ...
1、它们可以改变转录 2、看你的目标蛋白是谁?有些是别人研究过的，查Paper可得binding motif。PS：不...
We find that intra-motif dependencies are prevalent and not limited to first-order dependencies among directly adjacent nucleotides, but that second-order models appear to be the significantly better choice. The traditional PWM model appears to be indeed insufficient to infer realistic sequence motifs,...