5月22日《Cell》的颠覆性研究“The human proteome with direct physical access to DNA”,为我们打开了一扇通往DNA核心世界的新窗户——“零距离光交联”(zero-distance photo-crosslinking)技术!这项创新技术,犹如为分子生物学装上了...
5月22日《Cell》的颠覆性研究“The human proteome with direct physical access to DNA”,为我们打开了一扇通往DNA核心世界的新窗户——“零距离光交联”(zero-distance photo-crosslinking)技术!这项创新技术,犹如为分子生物学装上了高精度显微镜和高速摄像机,通过巧妙的代谢标记(metabolic labeling)和自主研发的高...
Allostery is a pervasive principle to regulate protein function. Growing evidence suggests that also DNA is capable of transmitting allosteric signals. Yet, whether and how DNA-mediated allostery plays a regulatory role in gene expression remained unclea
“Easy to use, intuitive interface makes working with sequences easy.” Matthew Nilles, University of North Dakota “I have never experienced a problem with this easy to use package…I recommended it highly.” Dr. Andrew M. Kropinski, University of Guelph ...
and also just .txt) into an image. A unique visualisation of DNA / RNA residing in text files, AminoSee is a way to render arbitrarily large files - due to support for streamed processing - into a static size PNG image. Special thanks and shot-outs to David Hilbert who invented it in...
Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends. Does also incise at AP sites in the DNA strand of DNA/RNA hybrids, single...
Using single-cell RNA-seq data from the Tabula Sapiens atlas37, we calculated a tissue/cell type expression specificity score (TCESS) for TFs in pairs demonstrating cooperativity and/or antagonism, where TFs with TCESS ~ 1 are ubiquitously expressed and higher values indicate greater tissue ...
血液RNA提取试剂盒(含DnaseI)关键词:血液RNA提取试剂盒,WK114,含DnaseI·AMCA标记兔抗山羊IgG二抗编号:WK405 英文名称:Donkey Anti-Goat IgG,AMCA Conjugated 规格:100μl 产品介绍:AMCA(7-Amino-4-methylcoumarin-3-acetic acid-NHS ester)是一种蓝色荧光素,与其它荧光素的荧光波长只有很小的重叠范围,和发出长...
The main objective of this trial is to explore the activity of chlorambucil, an alkylating agent commonly used in chronic lymphocytic leukemia treatment, in metastatic patients, gBRCA, including VUS, or DDR mutated, previously treated with a platinum-containing chemotherapy. ...
生物标记:可用于标记蛋白质、DNA/RNA等生物分子。 生物正交化学:通过与TCO等基团反应,实现生物正交标记。 荧光成像:适用于细胞成像、蛋白质定位等。 流式细胞术:可用于标记细胞表面或内部的特定分子。 药物递送系统:可用于实时监测药物递送过程。 注意事项: ...