Each box in a promoter contains an adenine–thymine (AT)-rich sequence (Fig. 1d). Such A-tracts are ubiquitous throughout all kingdoms of life, presumably due to their potential to curve DNA32,33. To assess the structural properties of the promoter, we engineered a set of comG promoters...
RNA Mass - Moles Converter Protein Mass - Moles Converter OD260to Concentration Mass Calculator from Molarity Dilution Calculator OD600Calculator Database ORF Search How to Use Vector Design Studio About VectorBuilder DNA Translation Input your DNA sequence below to retrieve the translated amino acid se...
transcription begins; (2) upon transcription, HT–T7RNAP pulls the opposing origami arm towards itself, forcing the structure to close; (3) when the terminator sequence is reached, the T7RNAP releases the dsDNA template linker, which causes the structure to actively open to its equilibrium ...
DNA The FASTA file to be analyzed. --amino=<aminoAcid> The amino acid representing the start of a gene. --find=<proteinFile> The DNA sequence to be found within the FASTA file. -h, --help Show this help message and exit. --max=<maxCount> The maximum count of the reading frame....
The DNA sequence information thereby obtained is used to synthesize each of the modified DNA aptamer molecules separately. By analyzing the binding characteristics of these aptamers, we can identify the most effective aptamer for the target protein. However, the amino-acid side chains are lost ...
Sequence-specific recognition of HIV-1 DNA with solid-state CRISPR-cas12a-assisted nanopores (SCAN) ACS Sens., 5 (5) (2020), pp. 1273-1280 CrossrefView in ScopusGoogle Scholar OKBA et al., 2020 N.M.A. Okba, M.A. Muller, W. Li, C. Wang, C.H. GeurtsvanKessel, V.M. Corman,...
sarcoma (FUS), zinc finger protein 706 (ZNF706), SERPINE mRNA binding protein 1 (SERBP1), and nucleolin (NCL) have all been reported to induce LLPS with G4 in vitro.10–13 G4 is a four-stranded, non-canonical, secondary structure of nucleic acids that forms in guanine-rich sequence...
While most TFs functioned exclusively as antagonists or antagonized TFs in our screen, 27 TFs participated in each role at different promoters, suggesting that the role of a given TF depends on its TF partner as well as the target DNA sequence (Fig. 3h). This is likely due to differences ...
The phrase "functional equivalents thereof" is intended to cover peptides which have a slightly altered amino acid sequence from that set out above, but which retain substantially the same biological activity. This may be achieved by various changes, such as insertions, deletions and substitutions,...
J. Patrick Fitch, Bahrad Sokhansanj, IEEE, Genomic Engineering: Moving Beyond DNS Sequence to Function, Proceedings of the IEEE, vol. 88, No. 12, Dec. 2000, pp. 1949-1971. Rudolf Hofmeister et al., New Photorefractive Mechanism in Centrosymmetric Crystals: A Strain-Coordinated Jahn-Teller ...