DNA is a what that encodes protein sequences? What are the structures of RNA and DNA and how might one be used to create the other? During the process of protein synthesis each tRNA carries one what? Which amino acid is coded by the mRNA sequence CAU?
All molecular biology is based on a central dogma: DNA codes for RNA which then codes for protein (amino acid) production. This concept is universal across all living organisms. Some biological entities will only possess RNA (like viruses, for example) but this p...
We conclude that the C-clamp is a sequence-specific DNA binding motif. C-clamp mutations destroy the ability of β-catenin to regulate the promoter, and they severely impair the ability of TCF-1 to regulate growth in colon cancer cells. Thus, E-tail isoforms of TCFs utilize two DNA ...
DNA, BacterialBacterial ProteinsCytoskeletal ProteinsSequence AlignmentBase SequencePoint MutationAmino Acid SequenceThe cell division protein FtsZ, essential to initiate septum formation in Escherichia coli, is a GTPase. The thermosensitive ftsZ84 mutation, which impairs the ability of FtsZ to bind and ...
(Fig.1b). Using GRIT, we also visualized the distribution of TAG sites throughout the 24 human chromosomes (Fig.1c). In addition to core functions related to recoding, GRIT can be used more generally for informatics involving coding DNA sequences, chromosomal sequences, gene essentiality, ...
Toward this goal, we discovered active halogenases from a DNA shuffle library generated from a halogenase–hydroxylase pair using a high-throughput in vivo fluorescent screen coupled to an alkyne-producing biosynthetic pathway. Insights from sequencing halogenation-active variants along with the crystal...
The two regions correspond to amino acids 1-274 and 274-425, and all but the C-terminal six residues were mutagenized during the PCR amplification by inherent infidelity of Taq DNA polymerase. Second, a lower concentration of dNTP (50 μM each instead of 200 μM each) and fewer cycles ...
activated transcription factor FOXO binds to conserved DNA-binding sequences within the dcr-1 promoter, directly suppressing its expression in reaction to nutritional scarcity. Our research demonstrates the importance of FOXO in managing nutrient reactions in the fat body, due to its suppression of ...
(Figure1). This granularity ranges from very fine, at the level of DNA microarrays (tens of bases in length, containing probe level information relevant to only a short region of the corresponding mRNA molecule) through coarser granularity with sequence reads (few hundreds), transcripts (...
Explain the process of RNA being translated into proteins. Does tRNA match up with the RNA to make codons? During transcription of mRNA what base pair changes? What happens during RNA splicing? The complementary mRNA strand synthesized from the DNA sequence of CTGAC would be ...