The invention relates to the pharmaceutical industry and to medicine, in particular to a novel highly active antioxidant which is used for preventing and treating diseases caused by oxidative stress and scarcity of oxygen in an organism and which is embodied in the form of a complex of a metal...
In recent years, a large number of basic and clinical studies have discovered that vitamin C has the protective role in a series of diseases caused by oxidative stress, such as cardiovascular disease, cancer and cirrhosis. Vitamin C can act as the superoxide scavenger in primary hypertension to...
4-hydroxy-2-nonenal mediates genotoxicity and bystander effects caused by Enterococcus faecalis-infected macrophages. Gastroenterology 2012; 142: 543–551 e7. CAS PubMed Google Scholar Esterbauer H, Schaur RJ, Zollner H . Chemistry and biochemistry of 4-hydroxynonenal, malonaldehyde and related ...
Oxidative stressBiomarkersChronic kidney diseaseExaggerated oxidative stress (OS) is usually considered as a disturbance in regular function of an organism. The excessive levels of OS mediators may lead to major damage within the organism's cells and tissues. Therefore, the OS-associated biomarkers ...
The present review we will discuss the dual character of tea polyphenols, both antioxidant and pro-oxidant properties, in some human diseases induced by oxidative stress. 展开 关键词: oxidative stress tea polyphenols antioxidant capacity pro-oxidant capacity ...
4-hydroxy-2-nonenal mediates genotoxicity and bystander effects caused by Enterococcus faecalis-infected macrophages. Gastroenterology 2012; 142: 543–551 e7. 4-hydroxynonenal and mechanisms of cell death S Dalleau et al 1627 7. Esterbauer H, Schaur RJ, Zollner H. Chemistry and biochemistry of ...
The development of hypothesis of oxidative stress in the 1980s stimulated the interest of biological and biomedical sciences that extends to this day. The contributions in this book provide the reader with the knowledge accumulated to date on the involvement of reactive oxygen species in different pa...
Oxidative stress has a key function in the pathogenesis of many infectious diseases, and represents moreover a promising strategy for chemotherapeutic development. Understanding the redox interactions and redox signaling mechanisms of pathogens and their hosts is crucial for developing (1) drugs that ...
ROS functions as a second messenger and modulates multiple signaling pathways under the physiological conditions. However, excessive intracellular ROS causes damage to the molecular components of the cell, which promotes the pathogenesis of various human diseases. Cardiovascular diseases are serious threats ...
Identification of a low-affinity, surface-located copper-binding site on SOD that is redox active and therefore could play some role in mediating redox-associated oxidative stress. CAS PubMed Google Scholar Bush, A. I. Is ALS caused by an altered oxidative activity of mutant superoxide ...