Recent studies have concluded that ROS damage has direct roles in the development and progression of many chronic diseases, including the pathogenesis of insulin resistance and type 2 diabetes. The link between
ETIOLOGY of diseasesOXIDATIVE stressPROTEOMICSBackground: Microtia is reported to be one of the most common congenital craniofacial malformations. Due to the complex etiology and the ethical barrier of embryonic study, the precise mechanisms of microtia remain unclear. Here we report a rare case of ...
Hcy is an excitatory amino acid, which markedly enhances the vulnerability of neurons to oxidative injury [3]. An elevated plasma level of Hcy (>14 μM) is termed as hyperhomocy-steinemia (HHcy), which has emerged as an independent risk factor for several neurodegenerative diseases such as...
Today, increased awareness of vascular diseases and access to tomographic imaging equipment facilitate the diagnosis of TAA, even when asymptomatic. While most TAA cases with ascending aortic involvement are treated with surgical repair (primarily valve-preserving techniques), aneurysms of the distal arch...
3.Objective: To study the relation of plasma Se to oxidative stress in the patients with primary glomerular diseases (PGS) and its clinical significance.目的: 观察原发性肾小球疾病(PGS)患者血浆硒(Se)、谷胱甘肽过氧化物酶(GSH-Px)、超氧化物歧化酶(SOD)和丙二醛(MDA)含量的变化及相互关系,探讨血硒...
Human malignancy is one of the most complex sets of diseases, representing an intersection of pathophysiology, genetics, and environmental factors, as well as immunology. Indeed, cancer represents not a single disease but a wide range of conditions with highly variable clinical courses ranging from ...
Therefore, clarifying the pathogenesis and targeting interventional therapy to slow down the progression of the disease is a key concern for clinicians. Currently, the etiology of NONFH has been considered to include coagulation disorders, abnormal lipid metabolism, oxidative stress, fat embolism, ...
The inclusion criteria were as follows: diagnosis of DoC based on the Coma Recovery Scale-Revised (CRS-R), condition persisting for over a month, sudden onset of DoC, and informed consent obtained from family members. Exclusion criteria were: neurodegenerative diseases, intracranial infections, post...
Toxic metals such as aluminium [20] and lead [21, 22] have been linked with numerous neurodegenerative diseases including AD, causing toxicity to multiple organs of the human body. Other elements such as copper and arsenic have been associated in experimental model systems with the disruption of...
Objective: To study the relation of plasma Se to oxidative stress in the patients with primary glomerular diseases (PGS) and its clinical significance. 目的: 观察原发性肾小球疾病(PGS)患者血浆硒(Se)、谷胱甘肽过氧化物酶(GSH-Px)、超氧化物歧化酶(SOD)和丙二醛(MDA)含量的变化及相互关系,探讨血硒...