Further development of these antioxidant molecules may be of value in preventing the development of neurodegenerative diseases.doi:10.1159/000025354Sun, Albert Y.Chen, Yong-MeiS. Karger AGJournal of Biomedical ScienceSun, A.Y., Chen, Y.M. (1998) Oxidative stress and neurodegenerative disorders. J...
Oxidative insults, whether over-excitation, excessive release of glutamate or ATP caused by stroke, ischemia or inflammation, exposure to ionizing radiation, heavy-metal ions or oxidized lipoproteins may initiate various signaling cascades leading to apoptotic cell death and neurodegenerative disorders. Amon...
Various environmental factors such as smoking and dietary habits are known to increase the risk for many diseases associated with aging. These factors link oxidative stress, cellular senescence, and microbial assault to the host. Oxidative stress has been associated with many aging disorders including ...
Parkinson’s disease (PD), and Alzheimer’s disease (AD), are far from being fully explained. Oxidative stress (OS) has been proposed as one factor that plays a potential role in the pathogenesis of neurodegenerative disorders. Clinical and preclinical studies indicate that neurodegenerative ...
Oxidative Stress, Sex, and Hypertension Oxidative Stress: A Unifying Mechanism in the Hypertension Mosaic Vasoactive Factors, Oxidative Stress, and the Vasculature Aldosterone, Oxidative Stress, and Hypertension Oxidative Stress and Inflammation in Hypertension Immunoinflammation, Oxidative Stress, and Hypertens...
Thorough presentation of these disorders with an emphasis on neurogenerative conditions but includes many others and is not limited to any one organ Part of the book series:Oxidative Stress in Applied Basic Research and Clinical Practice(OXISTRESS) ...
Metals, oxidative stress and neurodegenerative disorders The neurodegenerative diseases, Alzheimer's disease (AD) and Parkinson's disease (PD), are age-related disorders characterized by the deposition of abnorma... K Jomova,D Vondrakova,M Lawson,... - 《Molecular & Cellular Biochemistry》 被引...
Oxidative stress has been linked to a multitude of adverse health problems such as neurodegenerative diseases, inflammatory diseases, cardiovascular disease, diabetes, allergies, immune function disorders, aging, and cancer (Fig. 2) [12]. Reactive species are the products of mitochondrial metabolic ...
oxidative stress in toxicology and in the aetiology of several diseases, giving some consideration to the concept of risk factor and the use of biological responses as biomarkers. In this context, we will focus on biomarkers used in human studies. Finally, we will discuss the problem of ...
High levels of oxidative stress result in damage to sperm DNA, RNA transcripts, and telomeres and, therefore might provide a common underlying aetiology of male infertility and recurrent pregnancy loss, in addition to congenital malformations, complex neuropsychiatric disorders, and childhood cancers in ...