etc. Despite these numerous inconsistencies, it seems that oxidative stress is present in the course of psychiatric diseases. Still, it cannot be conclusively determined whether it is the direct cause of development, a consequence of other abnormalities at the biochemical or molecular level, or the...
Epigenetics in clinical practice. Examples in oxidative stress-related diseasesdoi:10.1016/j.freeradbiomed.2021.08.028Federico V. PallardoElsevier BVFree Radical Biology and Medicine
The present review we will discuss the dual character of tea polyphenols, both antioxidant and pro-oxidant properties, in some human diseases induced by oxidative stress. 展开 关键词: oxidative stress tea polyphenols antioxidant capacity pro-oxidant capacity ...
there are several hypotheses concerning the mechanisms that lead to the damage and death of brain cells in neurodegenerative diseases, such as excitotoxic effects by excitatory amino acids, disturbed cellular energy metabolism, and oxidative stress (OS),...
The “big three” infectious diseases HIV/AIDS, tuberculosis, and malaria were collectively responsible for nearly 260 million infected people in 2010. HIV, Mycobacterium tuberculosis, and Plasmodium falciparum, the causative agents of AIDS, tuberculosis
Infectious diseases are one of the most common threats for both domestic and wild animals, but little is known about the effects on the physiological condition and survival of wild animals. Here, we have tested for the first time in a wild vertebrate fac
pathogenesis, the development of compounds with improved mitochondrial targeting and enhanced antioxidant activity will be key to oxidative stress-based approaches to treating human cardiovascular diseases. In addition to new and more efficacious mitochondrial ROS scavenging compounds, given that ROS can ...
Oxidative stress and oxidative protein damage can accelerate the formation of toxic protein oligomers and aggregates in the nucleus and cytoplasm of nerve cells, which contributes to the pathogenesis of neurodegenerative diseases such as Alzheimer’s disease (AD), Parkinson’s disease (PD), Huntington...
Along with these conflicting evidences, it seems like the controversy about the oxidative stress theory in ageing and age-related diseases has never stopped (Fig. 2). In addition, over the past 30 years, fluctuations in the use of antioxidant supplements were also observed, for example in the...
Autophagy has been linked to cardiovascular diseases, as it is triggered by inflammation, hypoxia, oxidized lipoprotein, endoplasmic reticulum (ER) stress and reactive oxygen species (ROS), which are involved in atherogenesis [3], [4], [5]. Autophagy also promotes atherosclerotic plaque cell ...