Genetics can play a significant role, especially in cancers like chest adenocarcinoma, where mutations in genes like BRCA1 and BRCA2 increase risk. 4 How does adenocarcinoma spread? Like other cancers, adenocarcinoma can spread through the body via the lymphatic system or bloodstream, leading to me...
Higher cancer risk was related to BRCT domain of BRCA1 for breast cancer, and BRC repeats of BRCA2 for ovarian cancer. Parity was a risk-reducing factor among BRCA1/2 mutation carriers. Risk factors can be used for personalized preventive strategies of BRCA1/2 mutation carriers.Park, Ji ...
The article presents a study which examines the difference of triple negative breast cancer (TNBC), basal-like breast cancer (BLBC) and BRCA1 associated breast cancer (BABC). The study describes the pathology and biology of the three groups of tumor such as the definition of triple negative ...
Basal-like breast cancer was delineated using this methodology and demonstrates significant overlap with so-called triple negative and BRCA1-associated breast carcinomas. This article describes the pathology and biology of these three groups of tumours and examines the relationship between them. ...