We validated the increase of LCN2 secreted from four stromal cells induced by TNBC cells. Using a specific LCN2 antibody, we observed the inhibition of TNBC cell growth and migration. Taken together, these results propose secreted factors as molecular targets to treat TNBC progression via ...
Under basal conditions, endometrial epithelial and stromal cells exhibited cell type-specific profiles of secreted cytokines. Administration of hCG (100 IU) resulted in significantly (P < 0.05) different cytokine secretion profiles indicative of macropinocytic transport (HGF, MCSF) in epithelial ce...
Our study has identified a novel, non-contact-dependent LAK cell cytotoxic mechanism: induction of growth inhibition and programmed cell death due to endogenous NO synthesis in susceptible human cancer cells. 展开 关键词: fusion proteins antigen presentation vaccines peptide fragments antigenic ...
To isolate and culture adipose stromal cells (ASCs), and study the effect of cytokines secreted by ASCs on endothelial cells, human adipose tissue was digested with collagenase type I solution and ASCs were derived by culture. The cells surface phenotype was examined by flow cytometry. ELISA ...
Cytokines are polypeptides secreted by immune and other cells that carry signals to neighbouring cells to regulate the immune system. ___A.正确B.错误的答案是什么.用刷刷题APP,拍照搜索答疑.刷刷题(shuashuati.com)是专业的大学职业搜题找答案,刷题练习的工具.
摘要: Cytokines are a family of soluble secreted mediators produced by cells that effect the functioning of the same or other cells. Aspergillus fumigatus is a potent stimulator of cytokine and chemokine prDOI: 10.1007/1-4020-5492-0_9 年份: 2007 ...
to enhance T cell anti-tumor cytotoxicity are pivotal to improve treatment outcomes. By analyzing tumor samples from patients with head and neck or colon cancers, here the authors show that IL-12 can induce the expression of the inhibitory receptor NKG2A on tumor-reactive CD8 cytotoxic ...
Vinorelbine is one of the most active cytotoxic agents in breast cancer, especially metastatic breast cancer and bioinformat- ics analysis indicated that TGF-β signaling pathway may associate with drug resistance of breast cancer cells to vinorelbine [43]. The strong implication of TGF...
Evaluation of Secreted Cytokines by Multiplex Bead-Based Assay (X MAP Technology, Luminex) 来自 Springer 喜欢 0 阅读量: 57 作者:L Lombardelli,F Logiodice,O Kullolli,MP Piccinni 摘要: The Luminex XMAP technology permits the simultaneous evaluation of numerous cytokines in several types of ...
IL-4Adaptive immunityTh CellsCD124B cell, T cell, macrophagesProliferation of B and cytotoxic T cells, enhances MHC class II expression, stimulates IgG and IgE production IL-5Adaptive immunityTh2 Cells and mast cellsCDw125, 131Eosinophils, B-cellsB-cell proliferatio...