transcript variants encoding different isoforms have been found for this gene. 基因名:CYP2D6 别名:CPD6,CYP2D,CYP2D7AP,CYP2D7BP,CYP2D7P2,CYP2D8P2,CYP2DL1,CYPIID6,P450-DB1,P450C2D,P450DB1 基因ID:1565 Chromosome: (GRCh37)22Start:42522501End:42526908Strand:-1...
[2] Relationship of CYP2D6 genetic polymorphisms and the pharmacokinetics of tramadol in Chinese volunteers.[J]. J Clin Pharm Ther, 2010 Apr;35(2):239-47. [3] Effect of the CYP2D6 gene polymorphism on postoperative analgesia of tramadol in Han nationality nephrectomy patients.[J]. Eur J Cl...
transcript variants encoding different isoforms have been found for this gene. 基因名:CYP2D6 别名:CPD6,CYP2D,CYP2D7AP,CYP2D7BP,CYP2D7P2,CYP2D8P2,CYP2DL1,CYPIID6,P450-DB1,P450C2D,P450DB1 基因ID:1565 Chromosome: (GRCh37)22Start:42522501End:42526908Strand:-1...
Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2014] [中文简述(自动翻译):] 该基因编码的酶的细胞色素P450超家族的成员。细胞色素P450蛋白是能催化涉及药物代谢和胆固醇,类固醇和其他脂类的合成许多反应单加氧酶。此蛋白质定位于...
the poor metabolizer phenotype have no functional protein since they carry 2 null alleles whereas in other individuals the gene is absent. This gene can vary in copy number and individuals with the ultrarapid metabolizer phenotype can have 3 or more active copies of the gene. Alternatively ...
SOLUTION: This invention provides an assay method for screening a new variant of the cytochrome P4502D6 gene and these genotypes. The invention provides a detecting method for a polypeptide, primer, vector, host cell, antibody, agonist, antagonist, gene and protein chip and chemical sensitivity, ...
[001引进一步地,所述步骤S5中采用GENEMAPP邸ID V4.1软件对检测结果进行分析。[0014] 除此之外,本发明提供的CYP2D6基因多态性的引物在制备检测CYP2D6基因多态性 试剂中的用途。[0015] 与现有技术相比,本发明提供的技术方案具有W下优势:本发明提供了一种检测 CYP2D6基因多态性的引物,该引物的特异性好,不会发生...
This study aimed to determine the prevalence of genetic polymorphism in the CYP2D6 gene, which codes for the polymorphically expressed CYP2D6 drug-metaboli... AT Naveen,C Adithan,SS Soya,... - 《Biological & Pharmaceutical Bulletin》 被引量: 44发表: 2006年 Mutation frequencies of the cytochrom...
[4]Fukuda, T., et al. (2005). "Novel structure of the CYP2D6 gene that confuses genotyping for the CYP2D6*5 allele." Drug metabolism and pharmacokinetics vol. 20,5: 345-50. [5]Owen, R. P., et al. (2009). Cytochrome P450 2D6. Pharmacogenetics and genomics, 19(7),559-562. ...
CYP2D6不同变体或不同等位基因功能性定义 GENE:CYP2D6 NucleotidechangesNG_008376.3startingat ATG 14C>T 19G>A 31G>A 64delC Effectonprotein(NP_000097.3)A5V V7M V11M L22X PositionatNC_000022.11(Homosapienschromosome 22,GRCh38.p2)g.42130778G>A g.42130773C>T g.42130761C>T g.42130728del...