The cyclin-like protein SPY1 overrides reprogramming induced senescence through EZH2 mediated H3K27me3cell cycle genescellular reprogrammingcellular senescencehistone H3 methyltransferaseinduced pluripotent stem cellsFully differentiated cells can be reprogrammed through ectopic expression of key transcription ...
CALDERON MR; VERWAY M; AN BS;.Ligand-dependentcorepressor (LCoR) recruitment by Kruppel-like factor 6 (KLF6) regulates expression of the cyclin-dependent kinase inhibitor CD- KN1A gene.J Biol Chem.2012.8662-8674Calderon,M.R., Verway,M., An,B.S., DiFeo,A., Bismar,T.A., Ann,D.K....
This positive feedback loop of Clb1/2-Cdc28 activity and CLB1/2 transcription is presumed to help effect a switch-like decision to enter mitosis. Degradation of the Clb cyclins at the end of mitosis...Amon A, Tyers M, Futcher B & Nasmyth K (1993) Mechanisms that help the yeast cell...