This data reveals that the SPY1 protein is required for reprogramming to a pluripotent state and is capable of increasing reprogramming efficiency.doi:10.1002/stem.3453Dorota LubanskaIngrid QemoMegan ByrneKaitlyn N. MatthewsBre-Anne FifieldJillian Brown...
Spy1 is a novel 'cyclin-like' activator of the G1/S transition capable of enhancing cell proliferation as well as inhibiting apoptosis. Spy1 protein levels are tightly regulated during normal mammary development and forced overexpression in mammary mouse models accelerates mammary tumorigenesis. Methods...
Cyclin-Y-like protein 1 structure CAS No. Chemical Name: Cyclin-Y-like protein 1 Synonyms CCNYL1;Cyclin-Y-like protein 1;ANTI-CCYL1 (N-TERM) antibody produced in rabbit CBNumber: CB52907212 Molecular Formula: Molecular Weight: 0 MDL Number: ...
Substantially pure human cyclin-dependent kinase-like proteins PITALRE and PISSLRE and isolated protein complexes that comprise PITALRE or PISSLRE are disclosed. Isolated nucleic acid molecule that encode PITALRE or PISSLRE or a fragment thereof; recombinant expression vectors that comprise nucleic acid...
Volume 273, Number 2 (2000), in the article Molecular Cloning of a Cyclin-like Protein Associated with Cyclin-Dependent Kinase 3 (cdk 3) in Vivo, by Masaaki Matsuoka, Yoshiharu Matsuura, Kentaro Semba, and Ikuo Nishimoto, pages 442 447 (doi:10.1006/bbrc.2000.2965) ...
Over-expression of insulin-like growth factor binding protein-related protein-1(IGFBP-rP1/mac25) in the M12 prostate cancer cell line alters tumor growth b... protein-related protein-1(IGFBP-rP1/mac25) in the M12 prostate cancer cell line alters tumor growth by a delay in G1 and cyclin ...
1997. Differential expression of CAK (cdc2-activating kinase)-like protein kinase, cyclins and cdc2 genes from rice during the cell cycle and in response to gibberellin. Plant J. 11: 181–190. PubMed Google Scholar Savouré, A., Feher, A., Kalo, P., Petrovics, G., Csanadi, G., ...
Hippo信号通路在进化中高度保守,当细胞处于高密度生长或营养缺乏的环境中时,Hippo信号通路即被激活,MST激酶(mammalian sterile 20-like kinase)被磷酸化,在MOB1(Mps One Binder kinase activator protein 1,Mps一结合者激酶激活因子样1)蛋白的辅助...
We conclude we have probably isolated a dinoflagellate CDK5-like protein. The data reported here support the identification of this protein as a CDK5 homologue, and suggest that dinoflagellates may contain several CDK families. View Full Article (HTML) Enhanced Article (HTML) Get PDF (522K) More...
In S phase, CDK1 in complex with cyclin A2 increases FA size and stress fibre formation by phosphorylating formin-like protein 2 (FMNL2) and probably other FA and actin-associated proteins15,16. By contrast, in G2 phase, CDK1 is inactivated, which leads to a decrease in FA ...