Our results showed that the cyclin-like F-box domain (FBDC) formed the functional cluster with the lowest P-value. We also observed a significant expansion of FBDC families in V. volvacea. Among these, the FBDC3 family displayed the maximal gene expansion in V. volvacea. Gene expression ...
The cDNA encodes a protein that harbors a Ser/Thr protein kinase-like catalytic domain at the N-terminal. Hence, we named it GAK (cyclin G- associated kinase). The long C-terminal extension shares homology with tensin and auxilin, and contains a leucine zipper region. Co-immunoprecipitation ...
While MPF itself can phosphorylate Ser126 and Ser128, polo-like kinase 1 (PLK1) phosphorylates cyclin B1 preferentially at Ser133 and possibly at Ser147 (6,10). At the end of mitosis, cyclin B1 is targeted for degradation by the anaphase-promoting complex (APC), allowing for c...
Fig. 1. Human proteins containing a cyclin box or cyclin box-like domain. (a) Cladogram of human cyclin and cyclin-like proteins based on full-length sequences, displayed using UniProt name (UniProt codes with equivalent protein names and PFAM/InterPro domain assignments given in supplementary...
Here we show that cyclin I-like (CCNI2), a homolog of CCNI, interacts with CDK5 and activates the kinase activity of CDK5. Different from CCNI, which colocalizes with CDK5 in the nuclei in transfected cells, CCNI2 mainly retains CDK5 in the cytoplasm as well as on the cell membrane. ...
MSA-like sequences are also found in the promoters of G2/M-specific genes encoding kinesin-like proteins, suggesting that a defined set of G2/M-specific genes are co-regulated by a common MSA-mediated mechanism in plants. Thus, the molecular mechanisms regulating B-type cyclin gene ...
kinase domain, CDKs belong to the CMGC group of kinases (named for the initials of some members), along with mitogen- activated protein kinases (MAPKs), glycogen synthase kinase-3 beta (Gsk3β), members of the dual-specificity tyrosine-regulated kinase (DYRK) family and CDK-like kinases [...
kl399Mu01 白细胞**球蛋白样受体亚家族B成员4(LILRB4)多克隆抗体 Polyclonal Antibody to Leukocyte Immunoglobulin Like Receptor Subfamily B, Member 4 (LILRB4) kl401Mu01 原钙黏素β2(PCDHβ2)多克隆抗体 Polyclonal Antibody to Protocadherin Beta 2 (PCDHb2) kl525Mu01 巨噬细胞刺激1受体(MST1R)多克隆...
147539 EGFL7(EGF-like domain containing protein 7) 类表皮生长因子域7抗原 0.5mg147540 EGF(Epidermal growth factor)rat 重组表皮生长因子抗原(大鼠) 0.5mg147541 rhEGF(rh-Epidermal growth factor) 重组人表皮生长因子 100ug147542 ED-1 (Ectodermal Dysplasia 1) 外胚层发育不良抗原 0.5mg147543 ECP(...
In addition, several microRNAs like miR-4779, miR-212, miR-138, and miR-503 can destabilize cyclin D3 mRNA and block cell cycle progression in cell lines derived from colon cancer, T-cell leukemia/lymphoma, lung cancer, and hepatocellular carcinoma (HCC) [57–60]. Like cyclin D1, cyclin...