Single particle electron cryomicroscopy (cryo-EM) is a powerful method for determining the structures of biological macromolecules. With automated microscopes, cryo-EM data can often be obtained in a few days. However, processing cryo-EM image data to reveal heterogeneity in the protein structure ...
Single particle analysis cryo EM software for automated cryo electron microscopy data acquisition, enabling high-resolution 3D protein structure determination.
[7] T.A. M. Bharat, C. J. Russo, J. Lowe, L. A. Passmore, S. H. W. Scheres, Advancesin Single-Particle Electron Cryomicroscopy Structure Determination applied toSub-tomogram Averaging. Structure 23, 1743-1753 (2015).[8] B.A. Himes, P. Zhang, emClarity: software for high-resolu...
Single-particle electron cryo-microscopy (cryo-EM) is a powerful method for solving the three-dimensional structures of biological macromolecules. The technological development of transmission electron microscopes, detectors and automated procedures in combination with user-friendly image processing software and...
[7]T.A. M. Bharat, C. J. Russo, J. Lowe, L. A. Passmore, S. H. W. Scheres, Advancesin Single-Particle Electron Cryomicroscopy Structure Determination applied toSub-tomogram Averaging. Structure 23, 1743-1753 (2015). [8]B.A. Himes, P. Zhang, emClarity: software for high-resoluti...
[7]T.A. M. Bharat, C. J. Russo, J. Lowe, L. A. Passmore, S. H. W. Scheres, Advancesin Single-Particle Electron Cryomicroscopy Structure Determination applied toSub-tomogram Averaging. Structure 23, 1743-1753 (2015). [8]B.A. Himes, P....
CryoSPARC is a globally trusted complete solution for cryo-EM data processing Ultra-fast end-to-end processing of raw cryo-EM data and reconstruction of electron density maps, ready for ingestion into model building software Optimized algorithms and GPU acceleration at all stages, from pre-processing...
Both X-ray and cryo-EM structure determination represent “incomplete data problems,” where part of the data needed to determine the structure is considered to be missing. The missing data in X-ray diffraction experiments are the phases of the X-ray reflections; in cryo-EM the missing data ...
Advanced cryo-EM hardware and software The Glacios 2 Cryo-TEM comes equipped with AI-enabled software and state-of-the-art hardware, making it easier to obtain near atomic-resolution structures. Explore software and components Service and support for cryo-TEM instruments ...
Protein structure determination with cryo-EM Hear from scientists who are using the Glacios 2 Cryo-TEM in their research and take a closer look with our on-demand product tour. View videos and resources Advanced cryo-EM hardware and software The Glacios 2 Cryo-TEM comes equipped with AI-enab...