In cryo-electron microscopy (cryo-EM) data collection, locating a target object is error-prone. Here, we present a machine learning-based approach with a real-time object locator named yoneoLocr using YOLO, a well-known object detection system. Implementation shows its ...
Keep pace with data collection CryoSPARC Live™ is an extension of the CryoSPARC platform that enables real-time cryo-EM data quality assessment and decision making during live data collection, as well as an expedited, streamlined workflow for processing already available data. ...
In cryo-electron microscopy (cryo-EM) data collection, locating a target object is error-prone. Here, we present a machine learning-based approach with a real-time object locator named yoneoLocr using YOLO, a well-known object detection system. Implementation shows its effectiveness in rapidly ...
sample preparation and data collection cryo-em part a: sample preparation and data collection 1st edition, volume 481 - september 30, 2010 editor: grant jensen language: english hardback isbn: 9780123749062 9 7 8 - 0 - 1 2 - 3 7 4 9 0 6 - 2 ebook isbn: 9780080956954 9 7 8 - 0 ...
Cryo-electron microscopy (cryo-EM) captures snapshots of dynamic macromolecules, collectively illustrating the involved structural landscapes. This provides an exciting opportunity to explore the structural variations of macromolecules under study. Howev
Evolving suite of automation algorithms, – for simplifying screening and data collection (e.g., algorithm that auto-selects grid squares based on one user-selected candidate grid square) Intuitive user interface for smoother facilitation of new user training User interface of Smart EPU cryo ...
Everything needed for crystallization, crystal harvesting, cryocooling, & data collection Cryo-EM Tools Grids, equipment, and accessories for cryogenic electron microscopy sample prep Beamline Tools The tools you need to improve data collection methods at X-ray beamlines and home sources ...
Finally, we find that defocus range data collection is also applicable to VPP. This study shows that data processing and cryo-EM map interpretation, including atomic model refinement, are facilitated significantly by performing VPP cryo-EM.
The pasta puzzle: Decoding durum wheat’s DNA for a sustainable future An Italy that can’t grow its own wheat for pasta? It’s a race against time. Using a shared database in a Microsoft super‑computer, scientists from Italy and other countries are working together to develop new strai...
Data processingElectron microscopyThe dramatic growth in the use of cryo-electron microscopy (cryo-EM) to generate high-resolution structures of macromolecular complexes has changed the landscape of structural biology. The majority of structures deposited in the Electron Microscopy Data Bank (EMDB) at ...