Coding versus non-coding: translatability of short ORFs found in putative non-coding transcripts. Biochimie 93, 1981–1986 (2011). Article CAS PubMed Google Scholar Kapranov, P. et al. The majority of total nuclear-encoded non-ribosomal RNA in a human cell is 'dark matter' un-annotated ...
A. Decrypting noncoding RNA interactions, structures, and functional networks. Genome Res. 29, 1377–1388 (2019). CAS PubMed PubMed Central Google Scholar Lee, R. C., Feinbaum, R. L. & Ambros, V. The C. elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity...
Indeed, Sir2 suppresses non-codingRNA (ncRNA) formation from IGS1, which contains the bi-directional long non-coding (lncRNA) promoter, E-pro, as well as the RFB (Figure 1(a)). E-Pro is usually silenced by Sir2, thereby limiting RNAPII transcription and lncRNA accumulation [15,18,19...
Noncoding RNA blockade of autophagy is therapeutic in medullary thyroid cancer. Cancer Med. 2015; 4:174-182.J.S. Gundara, J. Zhao, A.J. et al., "Noncoding RNA blockade of autophagy is therapeutic in medullary thyroid cancer," Cancer medicine, vol. 4, no. 2, pp. 174-182, 2015....
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As in mouse, the human lncRNA is induced after DNA damage in a p53-dependent manner in the colon cancer cell line HCT116 (Figure 1B). We therefore named this lncRNA “noncoding RNA activated by DNA damage”, or NORAD. Despite its p53-dependent induction, we were unable to identify an...
Long Noncoding RNA Regulation of Pluripotency. Stem Cells Int. 2016;2016:1797692. PubMed Google Scholar Amaral PP, Mattick JS. Noncoding RNA in development. Mamm Genome. 2008;19(7–8):454–92. Article CAS PubMed Google Scholar Quinn JJ, Chang HY. Unique features of long non-coding ...
The expression of long noncoding RNA NEAT1 is reduced in schizophrenia and modulates oligodendrocytes transcription Article 25 June 2021 Background It has recently become evident that the majority of the mammalian genome is transcribed in a developmentally regulated manner producing tens of thousands of...
Green, D., Fraser, W. D. & Dalmay, T. Transfer RNA-derived small RNAs in the cancer transcriptome.Pflug. Arch.468, 1041–1047 (2016). CASGoogle Scholar Gibb, E. A., Brown, C. J. & Lam, W. L. The functional role of long non-coding RNA in human carcinomas.Mol. Cancer10, ...
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), a single-stranded positive ribonucleic acid (RNA) virus, is the causative agent, and multiple variants have emerged, ranging from alpha to omicron.3SARS-CoV-2, belonging to the Sarbecovirus subgenus of betacoronavirus, possesses a gen...