Coding versus non-coding: translatability of short ORFs found in putative non-coding transcripts. Biochimie 93, 1981–1986 (2011). Article CAS PubMed Google Scholar Kapranov, P. et al. The majority of total nuclear-encoded non-ribosomal RNA in a human cell is 'dark matter' un-annotated ...
A. Decrypting noncoding RNA interactions, structures, and functional networks. Genome Res. 29, 1377–1388 (2019). CAS PubMed PubMed Central Google Scholar Lee, R. C., Feinbaum, R. L. & Ambros, V. The C. elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity...
Noncoding RNA blockade of autophagy is therapeutic in medullary thyroid cancer. Cancer Med. 4 (2), 174e182.J. S. Gundara, J. T. Zhao, A. J. Gill et al., "Noncoding RNA blockade of autophagy is therapeutic in medullary thyroid cancer," Cancer Medicine, vol. 4, no. 2, pp. 174...
Noncoding RNAs (ncRNAs) have been assessed as biomarkers, and miRNAs have attracted most attention. More recently, other ncRNA classes have been identified, including long noncoding RNAs (lncRNAs) and circular RNAs (circRNAs). Here, we compare emerging ncRNA biomarkers in the cardiovascular field ...
Indeed, Sir2 suppresses non-codingRNA (ncRNA) formation from IGS1, which contains the bi-directional long non-coding (lncRNA) promoter, E-pro, as well as the RFB (Figure 1(a)). E-Pro is usually silenced by Sir2, thereby limiting RNAPII transcription and lncRNA accumulation [15,18,19...
Noncoding RNAs NEAT1: Nuclear paraspeckle assembly transcript 1 nt: Nucleotides PBMCs: Peripheral blood mononuclear cells Pol: RNA polymerase pre-miRNAs: Precursor miRNAs pri-miRNAs: Primary miRNA PTPN2: Tyrosine phosphatase non-receptor type 2 ...
cently,dualnoncodingtranscriptionbyalternativeRNA polymeraseswasimplicatedinepigeneticandchroma- tinconformationdynamics.Thisreviewintegratesthe currentknowledgeontheregulatorymechanismsacting throughplantnoncodingtranscription. Thecodingversusthenoncodinggenome Longbeforetheeraofnext-generationsequencingtechnol- ...
The expression of long noncoding RNA NEAT1 is reduced in schizophrenia and modulates oligodendrocytes transcription Background It has recently become evident that the majority of the mammalian genome is transcribed in a developmentally regulated manner producing tens of thousands of interleaved short and ...
Long Noncoding RNA Regulation of Pluripotency. Stem Cells Int. 2016;2016:1797692. PubMed Google Scholar Amaral PP, Mattick JS. Noncoding RNA in development. Mamm Genome. 2008;19(7–8):454–92. Article CAS PubMed Google Scholar Quinn JJ, Chang HY. Unique features of long non-coding ...
Second, the clusters have at least one noncoding RNA (ncRNA) that is usually expressed from the maternal allele and multiple paternally expressed protein-coding genes. Finally, the clusters are likely regulated by one of two mechanisms, transcription of a long ncRNA that silences expression of ...