TOLLEFSON GD, DELLVA MA, MATTLER CA, KANE JM, WIRSHING DA, KINON BJ. Controlled, double-blind investigation of the clozapine discontinuation symptoms with conversion to either olanzapine or placebo. The Collaborative Crossover Study Group. J Clin Psychopharmacol. 1999;19:435-43....
We further confirmed that the animals had learned to recognize specifically the interoceptive effects of clozapine and not simply any drug-induced state by testing several compounds with varying degrees of similarity to clozapine for their capacity to substitute for the clozapine stimulus. Olanzapine, wh...
At this point, an extensive medication reconciliation revealed the omission of clozapine. This information, together with her failure to improve and negative workup, lead to the suspicion of serotonin syndrome. Therefore, she was treated with a loading dose of 6 mg of cyproheptadine hydrochloride th...
Tollefson GD, Dellva MA, Mattler CA, Kane JM, Wirshing DA, Kinon BJ. Controlled double-blind investigation of the clozapine discontinuation symptoms with conversion to either olanzapine or placebo. The Collaborative Crossover Study Group. J Clin Psychopharmacol 1999;19(5):435-43....