cGMP-PKG signaling pathway Cyclic GMP (cGMP) is the intracellular second messenger that mediates the action of nitric oxide (NO) and natriuretic peptides (NPs), regulating a broad array of physiologic processes. The elevated intracellular cGMP level exerts its physiological action through two forms ...
This chapter focuses on the NO/cGMP/PKG signaling pathways involved in platelet inhibition. Platelets play a key role in normal and pathological hemostasis through their ability rapidly to adhere to activated or injured endothelium and subendothelial matrix proteins and to other activated platelets. A...
Activation of cGMP-PKG signaling pathway contributes to neuronal hyperexcitability and hyperalgesia after in vivo prolonged compression or in vitro acute ... ZJ Huang,LI Hao-Chuan,S Liu - 《Acta Physiologica Sinica》 被引量: 13发表: 2012年 Upregulation of Sodium Channel Nav1.3 and Functional In...
because of its reducing the source of myofibroblast which is dependent on its inhibitory effects on EMT. In this study, the airway epithelial cells and asthmatic mouse model with airway remodeling will be firstly used to explore the effects and molecular mechanism of ANP/cGMP/PKG signaling on ...
关键词:诱发簇放电;α-DTX 敏感钾电流 Part 1 NO-cGMP-PKG signaling pathway involved in sympathetic sensitization on DRG small sized neuron on CCD model Candidate for master: Hui-ming Li Supervisor: Jun-ling Xing Department of Neuroscience, Fourth Military Medical University, Xi’an 710032, China ...
Yanan Li, et al. A bio-inspired nanoparticle coating for vascular healing and immunomodulatory by cGMP-PKG and NF-kappa B signaling pathways. Biomaterials. 2023 DOI:10.1016/j.biomaterials.2023.122288 https://www.sciencedirect.com/science/article/pii/S014296122300296X...
Hervera A, Leanez S, Pol O: The inhibition of the nitric oxide- cGMP-PKG-JNK signaling pathway avoids the development of tolerance to the local antiallodynic effects produced by morphine during neuropathic pain. Eur J Pharmacol 2012; 685:42-51...
福建医科大学2010级硕士研究生毕业论文分类号:R541.4学校代码:10392学科专业代码:105101学号:2101003530福建医科大学硕士研究生毕业论文cGMP/PKG..
Yanan Li, et al. A bio-inspired nanoparticle coating for vascular healing and immunomodulatory by cGMP-PKG and NF-kappa B signaling pathways. Biomaterials. 2023 DOI:10.1016/j.biomaterials.2023.122288 https://www.sciencedirect.com/science/article/pii/S014296122300296X...
心血管疾病的发病机理较复杂，目前其机制尚未完全阐明，研究表明它的发病与多种因素有关，其中缺血再灌注损伤（ischemia-reperfusion，IR）是缺血性心血管疾病主要的病理过程[1]。已有研究显示,缺血再灌注过程中，通过激活eNOS-NO系统，从而激活下游的cGMP-PKG信号通路，实现对缺血性组织的保护。本文就eNOS-NO-cGMP-PKG...