cGMP-PKG signaling pathway Cyclic GMP (cGMP) is the intracellular second messenger that mediates the action of nitric oxide (NO) and natriuretic peptides (NPs), regulating a broad array of physiologic processes. The elevated intracellular cGMP level exerts its physiological action through two forms ...
Activation of cGMP-PKG signaling pathway contributes to neuronal hyperexcitability and hyperalgesia after in vivo prolonged compression or in vitro acute ... ZJ Huang,LI Hao-Chuan,S Liu - 《Acta Physiologica Sinica》 被引量: 13发表: 2012年 Upregulation of Sodium Channel Nav1.3 and Functional In...
This study thus suggested a novel NO/cGMP/PKG/5-HD-sensitive factor/ROS (H2O2) signaling pathway responsible for the NO/PKG-induced stimulation of pancreatic/neuronal-type KATP channels. 机译:ATP敏感性钾(KATP)通道由细胞内ATP和ADP控制,并用作代谢传感器,以将细胞的代谢状态和能量需求与细胞膜电...
内容提示: Contents lists available at ScienceDirectBBA - Molecular Basis of Diseasejournal homepage: www.elsevier.com/locate/bbadisGenes of the cGMP-PKG-Ca 2+ signaling pathway are alternatively spliced incardiomyopathy: Role of RBFOX2Xianxiu Wan a , KarryAnne Belanger b , Steven G. Widen b ...
NO-cGMP-PKG signaling pathway is involved in sympathetic sensitization. Keywords: sympathetic sensitization; norepinephrine; signaling pathway Part 2 The mechanisms of potassium channels underlying excitability of DRG neurons Presently, there are clear evidences that ectopic firing in injury nerve or DRG ...
Banxia Xiexin Decoction(半夏泻心汤) Treats Diabetic Gastroparesis through PLC-IP3-Ca2+/NO-cGMP-PKG Signal Pathway Objective:To test the effect of Banxia... 被引量: 0发表: 0年 Xiangshaliujunzi Decoction for the treatment of diabetic gastroparesis: A systematic review AIM:To assess the current...
Cardiac hypertrophy is an abnormal enlargement of heart muscle. It frequently results in congestive heart failure, which is a leading cause of human death. Previous studies demonstrated that the nitric oxide (NO), cyclic GMP (cGMP), and protein kinase G (PKG) signaling pathway can inhibit cardia...
These findings demonstrate that the beneficial effect of ICS II on neuronal cell proliferation, and its possible underlying mechanisms are, at least partly, through activating AKT/nNOS/NO/cGMP/PKG signaling pathway. Graphical abstract Download: Download high-res image (166KB) Download: Download full...
Note: cGMP-PKG, cGMP-dependent protein kinase (PKG) signaling pathway; ADRA1A, adrenoceptor alpha 1A; SLC8A1, solute carrier family 8 member A1; EDNRB, Endothelin Receptor Type B; ATP1A2, ATPase Na+/K+ transporting subunit alpha 2; KCNJ8, Potassium inwardly rectifying channel subfamily J mem...
www.nature.com/scientificreports OPEN received: 22 March 2016 accepted: 20 July 2016 Published: 11 August 2016 Urothelium muscarinic activation phosphorylates CBSSer227 via cGMP/PKG pathway causing human bladder relaxation through H2S production Roberta d'Emmanuele di Villa Bianca1,2,*, Emma...