关键词:诱发簇放电;α-DTX 敏感钾电流 Part 1 NO-cGMP-PKG signaling pathway involved in sympathetic sensitization on DRG small sized neuron on CCD model Candidate for master: Hui-ming Li Supervisor: Jun-ling Xing Department of Neuroscience, Fourth Military Medical University, Xi’an 710032, China ...
福建医科大学2010级硕士研究生毕业论文 分类号:R541.4学校代码:10392 学科专业代码:105101学号:2101003530 福建医科大学 硕士研究生毕业论文 cGMP/PKG信号通路在心肌缺血/再灌注损伤的作用机 制研究 AstudyonmechanismofcGMP/PKGsignalpathwaysin myocardialischemia/reperfusionInjury 学位类型: 医学硕士 所在学院:福建医科大学...
cGMP-PKG signaling pathway Cyclic GMP (cGMP) is the intracellular second messenger that mediates the action of nitric oxide (NO) and natriuretic peptides (NPs), regulating a broad array of physiologic processes. The elevated intracellular cGMP level exerts its physiological action through two forms ...
Tuina can exert immediate and continuous analgesic effects via the TRPV1 / TRPA1-NO-cGMP-PKG signaling pathway. Key words:three-manipulation and three-acupoint; neuropathic pain; TRP; cGMP; dorsal root ganglion; analgesic引用本文 杨震杰,萨出拉,于天源,张英琦,张润龙,陈金平,刘家玥,张汉钰,孙佳伟....
内容提示: Contents lists available at ScienceDirectBBA - Molecular Basis of Diseasejournal homepage: www.elsevier.com/locate/bbadisGenes of the cGMP-PKG-Ca 2+ signaling pathway are alternatively spliced incardiomyopathy: Role of RBFOX2Xianxiu Wan a , KarryAnne Belanger b , Steven G. Widen b ...
We conclude that changes in gene expression may influence the Ca2+ mobilization pathway in ChD, and AS impacts the genes involved in cGMP/PKG/Ca2+ signaling pathway in ChD and diabetes. Our findings suggest that ChD patients with diabetes may be at increased risk of cardiomyopathy and heart ...
Activation of cGMP-PKG signaling pathway contributes to neuronal hyperexcitability and hyperalgesia after in vivo prolonged compression or in vitro acute d... Activation of cGMP-PKG signaling pathway contributes to neuronal hyperexcitability and hyperalgesia after in vivo prolonged compression or in vitro...
本文就eNOS-NO-cGMP-PKG信号转导通路在缺血再灌注损伤过程中的作用及研究进展做一综述。1.缺血再灌注损伤的研究现状 1955年,Sewell结扎狗冠状动脉后,突然解除结扎,恢复血流,动物发生室颤而死亡。1960年,Jennings第一次提出心肌再灌注损伤的概念;1967年,Bulkley 和Hutchins发现冠脉搭桥血管再通后的病人发生心肌细胞...
Fig2 CyclicGMPsignalingpathway [ 23] · 1546 · 中国药理学通报 ChinesePharmacologicalBulletin 2010 Dec;26(12) 3.2 cGMP/PKG信号通路调节骨形成的作用 同样许多因素可以通过 cGMP/PKG信号途径对骨的形成进行调节。 NO、雌激素等可以通过调节 cGMP信号途径发挥调节骨形成的功能。雌激素对维持骨吸收和骨形成之间的...
NO-sGC-cGMP信号通路通过cGK调控PAI-2基因表达