2. cGMP/PKG信号通路的激活可以促进GSK-3β磷酸化。 【关键词】 心肌缺血/再灌注损伤 细胞凋亡 cGMP/PKG信号通路 mPTP GSK-3β 福建医科大学2010 级硕士研究生毕业论文 7 Part I The relationship between activation of the GMP/PKG signaling pathway and the RISK signaling ...
关键词:诱发簇放电;α-DTX 敏感钾电流 Part 1 NO-cGMP-PKG signaling pathway involved in sympathetic sensitization on DRG small sized neuron on CCD model Candidate for master: Hui-ming Li Supervisor: Jun-ling Xing Department of Neuroscience, Fourth Military Medical University, Xi’an 710032, China ...
第一部分背根节慢性压迫模型小细胞交感敏化的NO-cGMP-PKG信号通路 硕士研究生,李慧明 导师,**玲副教授 第四军医大学基础部神经生物学教研室,西安710032 中文摘要 交感维持性痛(SMP)是临床一种常见的慢性痛,SMP是指通过阻滞支配疼痛发生区域的交感神经而得到缓解的疼痛,这类疼痛常表现出依赖交感神经活动及循环中...
内容提示: Contents lists available at ScienceDirectBBA - Molecular Basis of Diseasejournal homepage: www.elsevier.com/locate/bbadisGenes of the cGMP-PKG-Ca 2+ signaling pathway are alternatively spliced incardiomyopathy: Role of RBFOX2Xianxiu Wan a , KarryAnne Belanger b , Steven G. Widen b ...
KEYWORDS: platelet aggregation; guanosine 3’,5’-cyclic monophosphate(cGMP); endothelial nitric oxide synthase(eNOS); NO; cGMP-dependent kinase(PKG); signaling pathway 基金项目:云南省科技厅地方本科高校基础研究项目(2018FH001-096) 作者简介:李青宴,女,硕士生 Tel: 18724983804 E-mail: 2240116487@qq....
cGMP-PKG signaling pathway Cyclic GMP (cGMP) is the intracellular second messenger that mediates the action of nitric oxide (NO) and natriuretic peptides (NPs), regulating a broad array of physiologic processes. The elevated intracellular cGMP level exerts its physiological action through two forms ...
Gastrodin improves hippocampal neurogenesis by NO-cGMP-PKG signaling pathway in cerebral ischemic mice 引用 收藏 分享 摘要 研究天麻素(gastrodin,GAS)对脑缺血后海马神经发生的作用,并探讨其与NO相关可能机制。利用双侧颈总动脉夹闭法建立C57BL/6小鼠脑缺血模型,分别用HE染色和Morris水迷宫检测海马CA1区的病理...
The nitrate reductase method was used to observe the NO content in the DRG of each group on the modeling side, and ELISA, Western blot, qPCR, and other methods were used to observe the changes in the protein and gene expression of the TRPV1/TRPA1-NO-cGMP-PKG signaling pathway in the ...
Sildenafil (Sil) increases cGMP and inhibits RhoA, and this intracellular pathway has pronounced effects on NHE3 activity. The aim of this work was to determine the effects of Sildenafil on NHE3 and to study the intracellular signaling pathway involved. The studies were performed by the ...
Activation of cGMP-PKG signaling pathway contributes to neuronal hyperexcitability and hyperalgesia after in vivo prolonged compression or in vitro acute d... Activation of cGMP-PKG signaling pathway contributes to neuronal hyperexcitability and hyperalgesia after in vivo prolonged compression or in vitro...