cGMP-PKG signaling pathway Cyclic GMP (cGMP) is the intracellular second messenger that mediates the action of nitric oxide (NO) and natriuretic peptides (NPs), regulating a broad array of physiologic processes. The elevated intracellular cGMP level exerts its physiological action through two forms ...
cGMP/PKG Signaling Suppresses Inositol 1,4,5-Trisphosphate Receptor Phosphorylation and Promotes Endoplasmic Reticulum Stress in Photoreceptors of CNG Channel-Deficient Mice: H. Ma, et al.; J. Biol. Chem. (2015), Application(s):ELISA using mouse retinal lysate,Abstract;Full Text Heterozygous NPR2...
cGMP/PKG Signaling Suppresses Inositol 1,4,5-Trisphosphate Receptor Phosphorylation and Promotes Endoplasmic Reticulum Stress in Photoreceptors of CNG Channel-Deficient Mice: H. Ma, et al.; J. Biol. Chem. (2015), Application(s):ELISA using mouse retinal lysate,Abstract;Full Text Heterozygous NPR2...
cGMP/PKG Signaling Suppresses Inositol 1,4,5-Trisphosphate Receptor Phosphorylation and Promotes Endoplasmic Reticulum Stress in Photoreceptors of CNG Channel-Deficient Mice: H. Ma, et al.; J. Biol. Chem. (2015), Application(s):ELISA using mouse retinal lysate,Abstract;Full Text Heterozygous NPR2...
Note: cGMP-PKG, cGMP-dependent protein kinase (PKG) signaling pathway; ADRA1A, adrenoceptor alpha 1A; SLC8A1, solute carrier family 8 member A1; EDNRB, Endothelin Receptor Type B; ATP1A2, ATPase Na+/K+ transporting subunit alpha 2; KCNJ8, Potassium inwardly rectifying channel subfamily J mem...
The administration of PDE5 inhibitors (PDE5Is) hindered fibroblast activation through suppressing autophagy by inhibiting the ERK signaling pathway. Conclusion: Our findings suggest that autophagy plays a pivotal role in promoting BPH progression through fibroblast activation, while PDE5Is effectively ...
江苏大学硕士学位论文 摘要 研究目的 检测II型cGMP依赖性蛋白激酶(cGMPdependentprotein kinase II,PKGII)在肿瘤细胞高表达对增殖相关信号转导通路MAPK/ERK的 影响。研究PKGII在基因调控中的作用。 研究方法 (1)构建携带PKGII基因的腺病毒载体。 (2)筛选对PKGII腺病毒感染敏感的胃癌细胞,感染PKGII腺病 毒,以8-pCP...
The inhibition of the nitric oxide-cGMP-PKG-JNK signaling pathway avoids the development of tolerance to the local antiallo- dynic effects produced by morphine during neuropathic pain. Eur J Pharmacol 2012;685(1-3):42-51.Pol,O.,Hervera,etc.The inhibition of the nitric oxide-cGMP-PKG-JNK ...
cGMP at the centre of attention: emerging strategies for activating the cardioprotective PKG pathway 喜欢 0 阅读量: 18 作者:Park,Min,Sandner,Peter,Krieg,Thomas 摘要: The nitric oxide (NO)-protein kinase G (PKG) pathw 年份: 2018 收藏 引用 批量引用 报错 分享 ...
Banxia Xiexin Decoction (半夏泻心汤) Treats Diabetic Gastroparesis through PLC-IP3-Ca2+/NO-cGMP-PKG Signal Pathway To test the effect of Banxia Xiexin Decoction (半夏泻心汤, BXD) on the contraction and relaxation of gastric smooth muscle (SM) in diabetic gastroparesis (... Bin Wang,Ke-wu...