the cGMP/PKG signaling pathway is associated with the activation of and ERK1/2 protein kinase. Methods: 84 New Zealandwhite rabbits were randomly divided into seven groups(n=12 in each group):sham group,control group,BNP group,BNP + LY294002 ...
Gastrodin improves hippocampal neurogenesis by NO-cGMP-PKG signaling pathway in cerebral ischemic mice 引用 收藏 分享 摘要 研究天麻素(gastrodin,GAS)对脑缺血后海马神经发生的作用,并探讨其与NO相关可能机制。利用双侧颈总动脉夹闭法建立C57BL/6小鼠脑缺血模型,分别用HE染色和Morris水迷宫检测海马CA1区的病理...
内容提示: Contents lists available at ScienceDirectBBA - Molecular Basis of Diseasejournal homepage: www.elsevier.com/locate/bbadisGenes of the cGMP-PKG-Ca 2+ signaling pathway are alternatively spliced incardiomyopathy: Role of RBFOX2Xianxiu Wan a , KarryAnne Belanger b , Steven G. Widen b ...
Here, we provide evidence supporting the idea that CCD or ADD treatment activates cGMP-PKA signaling pathway in the DRG neurons. The results showed that CCD or ADD results in increase of levels of cGMP concentration and expression of PKG-I mRNA, as well as PKG-I protein in DRG. CCD or ...
Ferulic acid ameliorates lipopolysaccharide-induced tracheal injury via cGMP/PKGII signaling pathway. Tracheal injury is a common clinical condition that still lacks an effective therapy at present. Stimulation of epithelial sodium channel (ENaC) increases ... X Xie,T Yu,Y Hou,... - 《Respiratory...
cGMP-PKG signaling pathway Cyclic GMP (cGMP) is the intracellular second messenger that mediates the action of nitric oxide (NO) and natriuretic peptides (NPs), regulating a broad array of physiologic processes. The elevated intracellular cGMP level exerts its physiological action through two forms ...
关键词:诱发簇放电;α-DTX 敏感钾电流 Part 1 NO-cGMP-PKG signaling pathway involved in sympathetic sensitization on DRG small sized neuron on CCD model Candidate for master: Hui-ming Li Supervisor: Jun-ling Xing Department of Neuroscience, Fourth Military Medical University, Xi’an 710032, China ...
研究表明eNOS-NO-cGMP-PKG信号转导通路在缺血再灌注损伤过程中发挥了重要作用。本文就eNOS-NO-cGMP-PKG信号转导通路在缺血再灌注损伤过程中的作用及研究进展做一综述。1.缺血再灌注损伤的研究现状 1955年，Sewell结扎狗冠状动脉后，突然解除结扎，恢复血流，动物发生室颤而死亡。1960年，Jennings第一次提出心肌再灌注...
This study thus suggested a novel NO/cGMP/PKG/5-HD-sensitive factor/ROS (H2O2) signaling pathway responsible for the NO/PKG-induced stimulation of pancreatic/neuronal-type KATP channels. 机译:ATP敏感性钾(KATP)通道由细胞内ATP和ADP控制,并用作代谢传感器,以将细胞的代谢状态和能量需求与细胞膜电...