cGMP/PKG信号通路在心肌缺血/再灌注损伤的作用机 制研究 AstudyonmechanismofcGMP/PKGsignalpathwaysin myocardialischemia/reperfusionInjury 学位类型: 医学硕士 所在学院:福建医科大学附属泉州市第一医院 研究生:潘国焰 学科、专业:内科学(心血管) 导师:**教授 ...
已有研究显示,缺血再灌注过程中，通过激活eNOS-NO系统，从而激活下游的cGMP-PKG信号通路，实现对缺血性组织的保护。本文就eNOS-NO-cGMP-PKG信号通路在心血管系统缺血再灌注损伤中的作用及研究进展作一综述。【关键词】缺血再灌注损伤一氧化氮合酶一氧化氮蛋白激酶G 信号通路 【中图分类号】R319 【文献标识码】A...
关键词:诱发簇放电;α-DTX 敏感钾电流 Part 1 NO-cGMP-PKG signaling pathway involved in sympathetic sensitization on DRG small sized neuron on CCD model Candidate for master: Hui-ming Li Supervisor: Jun-ling Xing Department of Neuroscience, Fourth Military Medical University, Xi’an 710032, China ...
内容提示: Contents lists available at ScienceDirectBBA - Molecular Basis of Diseasejournal homepage: www.elsevier.com/locate/bbadisGenes of the cGMP-PKG-Ca 2+ signaling pathway are alternatively spliced incardiomyopathy: Role of RBFOX2Xianxiu Wan a , KarryAnne Belanger b , Steven G. Widen b ...
cGMP-PKG signaling pathway Cyclic GMP (cGMP) is the intracellular second messenger that mediates the action of nitric oxide (NO) and natriuretic peptides (NPs), regulating a broad array of physiologic processes. The elevated intracellular cGMP level exerts its physiological action through two forms ...
Activation of cGMP-PKG signaling pathway contributes to neuronal hyperexcitability and hyperalgesia after in vivo prolonged compression or in vitro acute ... ZJ Huang,LI Hao-Chuan,S Liu - 《Acta Physiologica Sinica》 被引量: 13发表: 2012年 Upregulation of Sodium Channel Nav1.3 and Functional In...
Tuina can exert immediate and continuous analgesic effects via the TRPV1 / TRPA1-NO-cGMP-PKG signaling pathway. Key words:three-manipulation and three-acupoint; neuropathic pain; TRP; cGMP; dorsal root ganglion; analgesic引用本文 杨震杰,萨出拉,于天源,张英琦,张润龙,陈金平,刘家玥,张汉钰,孙佳伟....
NO–cGMP–PKG signalling pathway involved in the protection of cardiac myocytes during hypoxia/reoxygenationNO-cGMP-PKGhypoxia/re-oxygenationcardiac myocyteMicroRNAs (miRNAs) are a recently discovered class of similar to 22-nucleotide regulatory RNAs that post-transcriptionally regulate gene expression. We ...
环状AMP(cAMP)是重要的第二信使,在很多生物学效应中起作用。已知大量激素通过能将ATP转变成cAMP的腺苷酸环化酶去激活cAMP。cAMP与血管疾病,神经系统,免疫,细胞生长和分化,代谢等有关。 环状GMP一般比cAMP的含量水平低10~100倍,鸟苷酸环化酶作用在GTP上形成cGMP。一些激素,比如乙酰胆碱,胰岛素,催产素和其他特定的化...