D'Amelio M, Cavallucci V, Cecconi F (2010) Neuronal caspase-3 signaling: not only cell death. Cell Death Differ 17: 1104-1114.D'Amelio M, Cavallucci V, Cecconi F. Neuronal caspase-3 signaling: not only cell death. Cell Death Differ. 2010;17(7):1104-14. doi:10.1038/cdd.2009.180....
Western blot analysis of extracts from C6 (rat), NIH/3T3 (mouse), and Jurkat (human) cells, untreated or treated with Staurosporine #9953 (1 uM, 3 hr) or Etoposide #2200 (25 uM, 5 hr) as indicated, using Cleaved...
1010S Acetyl- and Phospho-Histone H3 (Lys9/Ser10) Blocking Peptide, 100 ug KIT Cell Signaling(CST) 1011S Cleaved Caspase-8 (Asp391) Blocking Peptide, 100 ug KIT Cell Signaling(CST) 1013S Jak1 Blocking Peptide, 100 ug KIT Cell Signaling(CST) 1015S EGR1 Blocking Peptide, 100 ug ...
Each control slide contains formalin fixed, paraffin-embedded Jurkat cells, both untreated and treated with etoposide, that serve as a control for cleaved caspase-3 (Asp 175) immunostaining. Western blot analysis was performed on extracts derived from the same cells to ve...
What are the key signaling proteins that correlate closely with tumor pyroptosis and apoptosis? How to find a balance point to utilize caspase-3/GSDME-mediated pyroptosis for cancer treatment and anti-tumor immunity? Introduction Cancer is a complex multifactorial disease with a high global mortality...
然而,在氧化应激条件下这一生物效应被逆转,TRPM2-S可以上调介导细胞凋亡的半胱氨酸蛋白酶cleaved caspase3加速RPLS细胞系的凋亡。这些生物学效应均与RPLS细胞内ROS水平的变化有明确的关系。该研究提示促进活性氧生成的疗法可能是潜在的TRPM2-S高...
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然而,在氧化应激条件下这一生物效应被逆转,TRPM2-S可以上调介导细胞凋亡的半胱氨酸蛋白酶cleaved caspase3加速RPLS细胞系的凋亡。这些生物学效应均与RPLS细胞内ROS水平的变化有明确的关系。该研究提示促进活性氧生成的疗法可能是潜在的TRPM2-S高表达度的RPLS患者的有效治疗手段之一。
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