Learn about the stages of the cell cycle and DNA damage repair in this informative poster and discover strategies for inducing cell death in cancer cells.
Our Cell Cycle & DNA Damage Repair poster summarizes the stages of the cell cycle and DNA repair. It also highlights strategies for enhancing replicative stress in cancer cells to force mitotic catastrophe and cell death.
Kaufmann NK and Kaufman DG (1993) Cell cycle control, DNA repair and initiation of carcinogenesis. FASEB J. 12: 1189 ± 1191Kaufmann WK, Kaufman DG. Cell cycle control, DNA repair and initiation of carcinogenesis. FASEB J 1993; 7:1188-1191....
This collection showcases ground-breaking cell cycle papers and reviews, ranging from basic discoveries to clinical applications.
细胞分裂(cell division)指细胞一分为二,产生两个遗传物质相同的细胞的过程。原核生物(prokaryotes)以二分裂(binary fission)的方式进行cell division。真核生物(eukaryotes)以有丝分裂(mitosis)的方式进行cell d…
Schroering AG, Edelbrock MA, Richards TJ, Williams KJ: The cell cycle and DNA mismatch repair. Exp Cell Res 2007, 313:292-304.Schroering AG, Edelbrock MA, Richards TJ, et al. The cell cycle and DNA mismatch repair[J]. Exper Cell Res, 2007, 313(2):292- 304....
A. (2017) Cell cycle-dependent phosphorylation regulates RECQL4 pathway choice and ubiquitination in DNA double-strand break repair. Nature communications 8, 2039Lu, H.; Shamanna, R.A.; de Freitas, J.K.; Okur, M.; Khadka, P.; Kulikowicz, T.; Holland, P.P.; Tian, J.; Croteau, ...
来自北京大学生命科学学院,加拿大西奈山医院等处的研究人员发表了题为“A Cell Cycle-Dependent Regulatory Circuit Composed of 53BP1-RIF1 and BRCA1-CtIP Controls DNA Repair Pathway Choice”的文章,发现了DNA双键断裂修复机制中的一个关键环节:53BP1的下游效应蛋白Rif1,由此找到了由RIF1和BRCA1主导的一种细胞...
细胞周期(cellcycle)是无论哪个考试局,哪个年级段都会涉及到的学习重点,涉及到对于多细胞生物的生长发育(growth and differentiaition),组织修复与再生(tissue repair and replacement),甚至是对于植物以及真菌类,原生生物的无性繁殖(asexual reproduction)都有非常重要的作用。
It has been established in yeast that the response to ionizing radiation is cell-cycle dependent. These observations can be interpreted in terms of variations in the ability to repair DNA double-strand breaks (DSB). In the present work, DSB repair was examined directly in synchronous yeast cultu...