24. Hedgehog Signaling Pathway 25. Hypoxia Pathway 26. IL-6 Pathway 27. Immune Checkpoint Signaling Pathway 28. Insulin Pathway 29. iPSC Differentiation Poster 30. JAK/STAT Signaling Pathway 31. JNK-MAPK Signaling Pathway 32. MAPK/ERK Signaling Pathway 33. Mitochondrial Apoptosis 34. Mitochondrial ...
The canonical transforming growth factor-β (TGF-β) signaling pathway is of great physiological importance. The process of TGF-β signal transduction is quite simple: an extracellular TGF-β signal (ligands, mainly TGF-β1) first interacts with specific membrane receptors (TGFBR1/2) and activates...
The mitogen-activated protein kinase (MAPK) pathway mediates signal transduction from cell surface receptors to downstream transcription factors that lead to cellular responses such as cell proliferation, growth, motility, survival and apoptosis. The role of MAPK pathway in cancer, immune disorders and ...
信号通路研究cell signal pathways Cell Signaling Technology, Inc (CST)是美国著名的生物公司和细胞信号转导研究的领袖,提供特色的信号转导检测用抗体及磷酸化抗体、ELISA试剂盒、激酶等产品。CST总部位于美国波士顿,毗邻哈佛、麻省理工等著名学府的雄厚人才资源,拥有专业的生产和研发队伍,发表的文章多次收录在Nature, ...
signal (TUNEL+, early stage of apoptosis) were always concomitant with elevated autophagic activity (clear LC3 puncta, LC3+), while LC3+TUNEL−cells were occasionally observed, indicating the remarkable concomitance of increased autophagy activity and apoptosis in the same LEC (Fig.1A, B). ...
图3. 细胞凋亡通路https://www.creative-bioarray.com/cell-apoptosis-assays.htm 王晓东实验室过去几十年一直在研究细胞凋亡和细胞坏死的生物化学通路。2019年8月13日,他们在Molecular Cell杂志发表了Estrogen-Related Hormones Induce Apopt...
Role of apoptosis signal-regulating kinase in regulation of the c-Jun N-terminal kinase pathway and apoptosis in sympathetic neurons. Mol Cell Biot 2000; 20:196–204. Article CAS Google Scholar Whitmarsh AJ, Cavanagh J, Tournier C, Yasuda J, Davis Ri. A mammalian scaffold complex that ...
oncogene-driven hyperproliferation→damage signal originates at collapsed replication forks DNA-SCARSs (DNA segments with chromatin alter- ations reinforcing senescence) :Senescent cells harbor persistent nuclear DNA damage foci 特点:associate with promyelocytic leukemian (PML) nuclear bodies (???) ...
Mitogen-activated protein kinases/extracellular signal-regulated kinase (MAPK/ERK) pathway is reported to be associated with the cell proliferation, differentiation, migration, senescence and apoptosis. The literatures were searched extensively and this review was performed to review the role of MAPK/ERK...
信号通路研究cellsignalpathways CellSignalingTechnology,Inc(CST)是美国著名的生物公司和细 胞信号转导研究的领袖,提供特色的信号转导检测用抗体及磷酸化抗 体、ELISA试剂盒、激酶等产品。CST总部位于美国波士顿,毗邻哈佛、 麻省理工等著名学府的雄厚人才资源,拥有专业的生产和研发队伍,发 ...